How much should the histology norm be? Histology, what is it in oncology

The tissue composition of one or another part of the uterus, its cervix, plays an important role in the diagnosis of various diseases, both associated and not associated with neoplasms in the organs of the reproductive system. For this reason, various studies of the cellular composition of tissues play such an important role in gynecology. It is precisely such studies that include uterine histology, which is carried out for various symptoms and can be informative in diagnosing various types of diseases.

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Definition

Histological examination of the endometrium and uterus is the study of the morphological cellular structure of certain tissue formations of a changed (or presumably changed) organ in order to establish the type of pathological process. In a situation where we are talking about the study of the reproductive system, the fundamental difference from a smear for cytology, which also considers the cellular composition, is that with cytology only a scraping of the upper layer of the mucous membrane is taken, while with histology - directly a piece of tissue (that is, the procedure more traumatic).

It is performed on patients of any age if there are sufficient indications for it. Unlike cytology, histology is not carried out for preventive purposes, as planned. The preparation for study is a fragment of tissue from a part of an organ, containing several cellular layers, cells of different types.

Its research is carried out using special solutions and dyes in laboratory conditions.

Indications

In what cases is cervical histology necessary? The following indications are available for this method:

  • Infertility;
  • Menstrual irregularities, absence of menstruation;
  • Stomach ache;
  • Pain and discomfort during sexual intercourse;
  • Excessively painful premenstrual syndrome;
  • Uncharacteristic or specific vaginal discharge;
  • Bleeding outside the menstrual cycle, etc.

Moreover, since the method is quite traumatic, it is prescribed only in cases where all other diagnostic methods turned out to be uninformative, did not help identify the disease, or there are significant contradictions between their results. In any case, an analysis for the histology of the cervix is ​​prescribed for the following conditions: leukoplakia, uneven surface of the cervical canal for unknown reasons, a large number of malignant atypical cells in a cytology smear, etc.

Contraindications

Although very often the histology of the endometrium of the uterus is studied, including for health reasons, in some conditions such an analysis cannot be carried out. It is recommended to postpone it if:

  1. The patient is pregnant;
  2. The patient has very low blood clotting;
  3. There is an acute inflammatory process in the organs of the reproductive system, as there is a high risk of infection;
  4. The patient has her period on the day of the proposed procedure.

Neglecting these contraindications may lead to bleeding and/or inflammation. A large scar may also form, which will negatively affect the distensibility of the birth canal, and therefore complicate the birth process in the future. Damage to the tumor formation can cause it to actively grow.

Preparations for the procedure

When preparing for this procedure, you need to undergo the following studies:

  1. Blood test for sexually transmitted diseases;
  2. Examination of the degree of vaginal cleanliness;
  3. Cytological examination, bacteriology, PCR;
  4. You must not have sexual intercourse for 48 hours before the intervention;
  5. During the same time, tampons, douching, vaginal suppositories, gels, creams, etc. cannot be used;
  6. In consultation with your doctor, you should stop taking anticoagulants and hormonal drugs.

Correct and complete preparatory measures before the intervention are very important, as they significantly affect the information content and objectivity of the data obtained during the analysis.

What day is it due?

The stage of the menstrual cycle at which the cervical histology analysis is taken depends on the purpose for which the study is being carried out. When determining certain indicators, it is better to choose one or another day to conduct this study.

  • To diagnose menorrhagia, it is recommended to collect research material no later than 48 and no earlier than 72 hours before the expected start of menstruation;
  • When determining the causes of infertility, this period increases to 5-7 days;
  • If it is necessary to assess the hormonal status based on the results of scraping, then it is better to do it in the third stage of the menstrual cycle, since it is during this period that its results are most objective and informative (from 17 to 25 days of the cycle);
  • If amenorrhea occurs, then tests are usually taken several times - four times with a week's break between them (usually, low-traumatic methods are used);
  • If diagnosis is necessary in the presence of any tumors, then the results of cervical histology are equally informative, regardless of the period in which they were given.

There may be some other features. That is why it is very important to take a histological analysis exactly when the doctor prescribed it. If it is prescribed urgently, then when decoding the specialist must make allowances for the stage of the menstrual cycle at which the study was carried out.

Collection methods

Material from the uterine cavity can be collected in various ways. Typically, 8 of them are most often used. Some are more traumatic, others less. The most appropriate method is selected by the doctor, based on the individual characteristics of the patient’s body. The most popular methods are:

The least traumatic methods include laser and radio wave. They are most often prescribed to young girls. The simplest and cheapest, as well as traumatic, methods are those that use a simple scalpel or loop. Using this method, the procedure is usually carried out free of charge, under a compulsory health insurance policy.

Progress of the study

After the drug has been taken for research, it is treated with a preservative, as well as coloring compounds to simplify diagnosis. Water is removed from the preparation, which also makes it more durable and its morphology easier to evaluate.

A dense block of fabric is made using paraffin. Then a thin section of the tissue is taken under a microscope using a special device. The material is colored along the cut in one way or another. After this, the tissue section is examined under a microscope. Normally, the epithelium is brown, the cells are approximately the same. If there are deviations, this suggests the presence of a particular disease.

Peculiarities

Everyone undergoing this analysis should take into account that although histological examination of the cervix is ​​a fairly common procedure that is prescribed more or less regularly, it is nevertheless complex. Therefore, the professionalism of the specialist who performs it plays an important role in its informativeness and the quality of the result. This is especially true for the most innovative methods of work, in which doctors do not yet have sufficient experience (compared to old methods).

In addition, high-quality preparation for such an analysis on the part of the patient is very important. All recommendations must be followed in full. Only then will the test result be as effective as possible.

Production time

How long does this analysis take? Production time varies and depends on many parameters. These are the workload of the laboratory, and the peculiarities of the methods by which the material is studied, and the goals of the study, and the characteristics of the drug, etc. but on average, the results of the study can be obtained 3-7 days after delivery.

Decoding

How to decipher the results? Only a doctor can do this correctly. It is possible to establish whether atypia is only of a background nature, or whether it affects the deeper layers of tissue and atypical cells are present not only on the mucosa, but also in deeper layers. If atypical cells are found in the deep layers of tissue, this makes it possible to assume or confirm the presence of invasive cancer - the most severe form of oncology.

Are there mistakes?

Can a bad biopsy be wrong? More often than not, a good biopsy is erroneous when, due to an error in tissue sampling or examination, atypical cells are not detected, although in fact they are there. In general, if the preparations and techniques for sampling and studying were followed, then the likelihood of error is very low.

Recovery period

Taking into account the method used to collect tissue for study, the recovery period may vary in duration. Typically, it is recommended that you follow the restrictions listed below for three to six weeks after the intervention. The minimum indicator is recommended for low-traumatic interventions, the maximum for fairly traumatic ones. What restrictions do experts recommend observing during this period?

  1. For 5-7 days, do not lift heavy objects and limit physical activity;
  2. For 3 days, it is better to avoid getting water into the vagina;
  3. During the entire recovery period, you should not swim in natural reservoirs or chlorinated public pools, as there is a risk of infection;
  4. You should not steam in saunas, sunbathe, or visit a solarium during the entire recovery period;
  5. You can begin sexual activity again no earlier than a month after the intervention, regardless of its type.

Normally, when such an intervention is performed, slight bleeding from the vagina and mild nagging pain in the lower abdomen may be observed for a week. This is normal. However, if the pain becomes too intense, the discharge becomes uncharacteristic - changes in smell and color, or there is severe bleeding, then you should immediately consult a doctor. The same should be done if there is an elevated body temperature.

Price

The cost of the study varies in different cities.

Prices are indicative and may be increased due to the cost of materials and medications.

Conclusion

Although histology analysis is quite traumatic, it is nevertheless necessary. And if done in a timely manner, it can even indirectly contribute to saving the patient’s life.

Histological analysis is the examination of tissue taken from an organ for a more accurate diagnosis. Today, this is the most reliable research method; it is very important, one might say, of paramount importance for establishing a diagnosis and determining a treatment method.

What does the histology analysis show? Most often, histological analysis is carried out to identify inflammatory processes in the digestive system, to determine the causes of infertility, to diagnose oncology, to identify pathological processes in the uterus and other female organs, to determine the correct therapy for diseases of the internal organs. Histological studies are based on the study of tissue under an optical microscope, which not only determines the type of tumor, but also provides a lot of information about its characteristics.

Histology is a science whose subject of study is the tissues of the human body. Tissue analysis helps to detect a pathological process at the cellular level, that is, at the very beginning of its formation. In this way, it is possible to identify the initial stages of the tumor and structural mutational processes. Special equipment helps to accurately identify foreign bodies and study their characteristics in detail.

The tissues of the human body provide specialists with a huge amount of information about the functioning of the body both as a whole and in places of pathology. If biopsy, as well as histology, is carried out in a timely manner, then conservative treatment of diseases is possible at an early stage.

The basics of histology are, as already mentioned, tissues. Tissue is cells and intercellular substance that have the same structure and origin. The intercellular substance may either contain fibers or have a gel consistency.

In total, there are 4 types of tissues in the human body - nervous, muscle, connective and epithelial. Blood and lymph are also considered tissues; we can say that they are the fifth type of tissue. Over the course of a person’s life, tissues undergo age-related changes, they wear out, and cells can die or be restored. Often, neoplasms develop on tissues, which in turn also consist of tissues, so we can say that the main task of diagnostic histology is to distinguish benign from malignant formations and to identify cancers in a timely manner.

As a rule, histological diagnosis is the final stage of diagnostic measures. First, the patient undergoes an MRI, CT, ultrasound, x-ray, and so on, and only then undergoes a histology analysis to confirm the diagnosis. Thus, all preliminary diagnostics only revealed a neoplasm in tissues, but could not give an accurate determination of whether it is malignant or benign, and only histological analysis establishes the verdict. In addition, in some cases, post-therapeutic histology is required to determine whether the treatment was effective.

How is the analysis carried out?

Everyone knows how to take a blood test, but how to do histology, how long does it take? Histology can be carried out in several ways - the study can be carried out using blood, secretions, or directly studying the tissues themselves. A histological smear is done in urology and gynecology. Therefore, the analysis may be carried out in different ways, but the quality of diagnosis is the same in any case.

If it is necessary to conduct an examination of internal organs, painkillers may be required; painless procedures (for example, smears) are performed without anesthesia. Some types of research are carried out in a clinic, others can only be done in a hospital setting.

The skin and its derivatives are also subject to histological analysis; it is indicated if there are formations on the skin (moles, etc.). The analysis differentiates benign from malignant formations, and also determines the presence or absence of an inflammatory process.

Endocrinology in some cases may also require histological analysis. The endocrine system and histology are associated with each other mainly in the presence of a tumor in the endocrine glands of internal secretion. Gynecology, genitourinary system, digestive system, skin - these are the most common examples where histological analysis is carried out.

How long does a histology analysis take? On average, the analysis takes from a week to 10 days after the test sample is received, however, it all depends on whether the clinic has the necessary equipment. So you need to check the timing directly with the medical institution.

There is a rapid analysis that is done during surgery. If tumors are detected during surgery, a sample of them can be examined under a microscope in a short period of time. If a malignant tumor is confirmed, the surgeon decides on a more extensive operation, taking into account all the nuances of removing the malignant tumor.

A description of the results is given to the patient in writing; only a person with a medical education can decipher it; as a result, no recommendations are given, so it is necessary to consult a doctor to decipher it and determine further actions.

Histology of the oral cavity

There is a textbook “Histology in diagrams and tables”, it is intended for students and specialists in this field. It clearly describes the structure of the oral cavity, including in diagrams, lists and tables. Very briefly, the histology of the oral cavity is as follows.

If we approach the structure of the oral cavity from the point of view of histology, then for the most part its organs are covered with mucous membrane. The oral cavity has a basic lamina and an epithelial layer, which consists of squamous epithelial cells. As for the plate, these are connective tissues.

Lips are also an oral cavity; essentially they are folds of skin that have an outer and inner surface. The outside of the lips is covered with fibrous connective tissue, and the inner surface is epithelial, it has outgrowths (papillae). The lips are based on the circular muscle - that is, muscle striated tissue.

The cheeks also belong to the oral cavity - their inner membrane is epithelial tissue, the middle one is muscle fibers, and the outer one is connective tissue. As for the salivary glands, they are located in the connective tissue.

In the oral cavity there is a palatine arch, it fuses with the bony palate and has a main plate and epithelial tissue with a layer of palatine veins. The soft palate in the oral cavity limits it from the pharynx, it also consists of epithelial tissue. The palatine tonsils are located in the submucosa.

The palatine tonsils consist of parenchymal tissue and stroma.

The parotid glands are composed of connective tissue that is rich in collagen fibers. As for the submandibular gland, it is also connective tissue, and it has a very well developed duct system. The sublingual gland is mainly mucous tissue, but its septa are again composed of connective tissue.

The oral cavity also contains a muscular organ – the tongue. It is formed from striated muscle tissue. However, the tongue also has a mucous membrane, which forms protrusions - papillae. However, the root of the tongue does not have papillae; it is covered with tonsillar tissue, from which the lingual tonsil, which has follicles, is formed. The space between the follicles is filled with lymphoid tissue. The tongue is penetrated by three glands - mucous, protein and mixed. The dorsum of the tongue has no submucosa.

The larynx is a section of the respiratory tube, thanks to which the trachea connects to the pharynx. The cartilages of the larynx are connected to each other by connective tissue, in addition, the larynx contains muscle tissue and mucous membrane.

The trachea is a cartilaginous tube, at the top it is connected to the larynx, and at the bottom it is divided into the main bronchi.

The gums consist of a lamina propria and epithelial multilayered and heavily keratinized tissue. The main plate contains many vessels and elastic fibers. The main tissue of the tooth is dentin - this is one of the types of bone tissue that is characterized by high density. In addition, the tooth structure contains enamel, cement and pulp.

Histological examination helps to accurately determine the presence of dangerous cells and neoplasms. Histology is carried out to study tissues of different organs and systems. The difference between this research method and others is the increased accuracy of obtaining results.

Modern examinations of the body are carried out in different ways: examinations, tests, ultrasound. But these methods do not always allow an accurate diagnosis or detection of pathogenic cells and foreign formations. There is a more accurate method for this called histology. Many have heard about a smear for histology, but not everyone knows what it is.

The histological research method makes it possible to study cells and tissues and identify developmental pathologies. This method is often used in gynecology and other areas of medicine. If you do not know what a histology analysis means, how it is done, and what results it shows, we will help you figure it out.

How is a histology analysis done?

Many people do not know how to take a histology test. The study is unlike any conventional research method. Depending on which organ needs to be checked, the form of analysis varies: smears, prints, sections or tissue films. The analysis algorithm must be accurate and all research rules must be followed.

After the doctor receives a piece of tissue, it must be placed in formalin or ethanol, cut into a thin section and stained using special means. Methods for dyeing cut fabrics also vary. The most commonly used is hematoxylin and eosin. Due to exposure to dyes, the color of the fabric composition changes.

For example, hematoxylin colors nucleic acids blue, and with its help proteins turn red. After the procedures are completed, the specialist examines the prepared sample using an electron microscope for the presence of pathogenic and dangerous cells. But there is another way to perform histology.

In some cases, tissue sections are placed in a special balm or paraffin, and the resulting samples can be stored. And, if possible, conduct research using various microscopes: light, scanning, electronic, fluorescent and others. Using a phase contrast microscope allows you to view images of samples that cannot be seen using conventional microscopy.

The required tissue sample is collected using a puncture needle, bone trephination, or aspiration.

What does the histology analysis show?

This analysis is not always required. Why is histology done? Histology is necessary in the following cases:

  • To determine the presence of cancerous tumors in the body, this is the most common reason why a histological examination is performed. Studying tissues using this method allows you to determine whether there are dangerous cells in the body;
  • To identify the causes of infertility;
  • To study the condition of the female genitourinary system;
  • To determine the inflammatory process in the organs of the digestive system.

How long does a histology analysis take?

To the question of how long it takes to perform histology, each clinic gives its own answer. On average, the result of the study becomes known 7-10 days after taking a tissue sample. The time it takes to obtain the result also depends on the availability of your own laboratory on the territory of the medical institution. With the existing laboratory, the time required for performing histology is significantly reduced. When ordering a histological examination from a third-party laboratory, delivery of the result may take 2-3 days or more. There is also express diagnostics, which is carried out in the operating room.

If during surgery a patient is suspected of having malignant tumors, a tissue sample can be examined under a microscope in a short period of time. If the result is positive, the surgeon must perform an extended operation, taking into account the rules for removing oncological formations.

Results and interpretation of histology analysis

The results of histology tests are given to the patient in the form of a written report. It will indicate whether there are abnormalities in cells and tissues. But not everyone will be able to decipher the result. To correctly interpret histology tests, you must at least have a medical education. Information about the study is provided in Latin using medical terms.

If you had a histological examination performed at a government institution on the direction of a doctor, you will be able to find out about the results at his appointment.

When you contact a private medical clinic, you will receive a conclusion in your hands. The form will contain the following information:

  • patient's personal data;
  • what type of tissue was taken for study;
  • sample collection site.

Next, the method and time of the study are indicated. What solutions were used to study the tissue samples taken - information is also indicated in the form. The main conclusion about the histology parameters is described at the very end. Don't worry if you see a lot of information. This does not mean that many abnormalities or pathologies have been found.

The specialist who conducted the study lists not only possible tumors, but also the detection of all tissues. You are unlikely to read the conclusion in Latin on your own. Therefore, after receiving the test results, consult a doctor, who will also advise you on possible treatment or preventive measures.

Regardless of whether the histology results may be positive or negative, no recommendations are indicated in the conclusion.

Can a histology test be wrong?

Many patients, after receiving a histological conclusion about the presence of a malignant tumor, want the result to be erroneous. But, unfortunately, errors in histology are extremely rare. This research method is considered the most accurate and, in some studies, allows not only to determine the presence of malignant cells, but also the cause of their appearance.

Despite the accuracy of the histological method, experts do not deny that there is a small percentage of incorrect and inaccurate studies. But if the procedure for taking a tissue sample and the algorithm of action during the study were followed, then the result cannot be erroneous.

Histology is considered one of the most reliable and informative ways to recognize a female disease.

This analysis is used after unexpected miscarriages, during a frozen pregnancy, when there are suspicions of cancer, and in other difficult cases.

Today, histology in gynecology is an indispensable tool that allows us to identify even complex pathologies.

What is histology?

Histology is the science of the state of the body at the tissue level.

The analysis is closely related to cytology (the study of cells) and embryology (the study of the structure of the fetus) and allows one to study the exact structure of any tissue, so it is often prescribed to identify various abnormalities and pathologies.

To conduct a histological examination, a small piece of tissue is taken from a person: sometimes it is just a smear or print, but it can also be a thin section directly from the organ being examined.

The study lasts on average 5-10 days (in rare cases, urgent histology is performed from 1 to 24 hours, but it is less reliable) and is carried out in 7 stages:

  • Fixation– the tissue fragment is treated with a liquid that prevents the breakdown of cells and structures so that the material does not rot during the study.
  • Wiring– the material is dewatered for compaction.
  • Fill– the tissue is impregnated with paraffin or another embedding preparation to prepare a solid block for obtaining sections.
  • Cutting– using special equipment – ​​a microtome – the solid block is cut into the thinnest plates.
  • Coloring– sections are laid out on glass slides and stained with special preparations to determine different tissue structures (DNA, RNA, cytoplasm, etc.).
  • Conclusion– prepared sections on glass slides are covered with a second layer of glass with the medium necessary to preserve the material for a long time.
  • Study– the resulting histological preparations are studied by histologists or pathomorphologists using an electron or light microscope.

In gynecology, histology is usually prescribed to study tissues of the fetus, uterus and cervix.

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Histological examination of a frozen pregnancy or after a miscarriage

A frozen pregnancy in the medical sense is the same miscarriage, it just hasn’t happened yet. In both cases, the doctor cleanses the uterus to avoid rotting of the embryo in the female body, which can lead to inflammation and severe illness.

The extracted material (placenta) must be sent for histological examination.

Histology after a miscarriage in combination with testing for viruses, hormonal imbalance, etc. helps determine the exact cause of spontaneous abortion or fetal death in the womb. Knowing the cause will help you avoid recurrence of problems during your next pregnancy.

Histology for determining gynecological oncological diseases

It can be very difficult to determine the presence of cancer - often in the initial stages they are asymptomatic, so it becomes almost impossible to notice and manage to prevent their development. However, with regular visits to the gynecologist, it is possible to recognize the emerging disease. During the examination, the doctor will notice symptoms that the woman does not feel and will prescribe a histology of the affected organ.

The study allows not only to identify the pathology, but also to carry out the correct treatment: histology shows the category of the neoplasm - benign or malignant.

Histology of the uterus

To prescribe uterine histology, more noticeable symptoms and other studies are often necessary (Ultrasound, blood test, etc.). Symptoms for which histology is prescribed include:

  • prolonged bleeding;
  • causeless pain in the lower abdomen;
  • leukoplakia;
  • irregularities on the surface of the organ;
  • neoplasms on or inside an organ and other symptoms related to tumor diseases.

Under sterile conditions under local anesthesia, the doctor uses gynecological instruments to cut out a piece of the tumor directly from the uterus. The tissue is sent to the pathology laboratory, where it is examined.

If abnormal tissue areas are detected, appropriate gynecological oncological treatment against cancer is prescribed. If the tumor tissue is homogeneous with the tissues of a healthy uterus, then the disease is benign (most often it is fibroids) and it can either be treated or wait until it goes away on its own (in some cases it does) - the gynecologist reports the exact decision.

Ovarian histology

It is carried out to determine the contents of cystic neoplasms on the ovaries or the type of tumor growths. To select the material, a puncture (puncture) is used through the abdominal cavity.

Histology of the cervix

If inflammatory, precancerous or oncological diseases of the cervix are suspected, the gynecologist sends a small piece of it for histology.

The study helps determine the presence of erosion, dysplasia, flat condylomas, cancer and other diseases of the cervix, so that the gynecologist can prescribe correct and effective treatment.

The material is collected in the same way as from the uterus, but there is no need to dilate the cervix.

Other types of histology in gynecology

For histological examination to identify health problems in the female reproductive system, endometrial tissue, part of the mucous membrane from the cervical canal, and fluid from cystic formations in the vagina taken by puncture can be sent.

Histology: analysis transcript

When filling out a sheet with research results, they use medical terms that are difficult for ordinary people to understand, and often the most unpleasant things from these terms are written in Latin.

The histology results are sent to the gynecologist, and based on them he will make a diagnosis and prescribe the correct treatment. It is not recommended to decipher the analysis yourself, so as not to make yourself think about terrible diseases.

Almost all diseases today are curable, so it is better to rely on a doctor and his experience.

Histological examination of neoplasms is an analysis of tissue taken from the patient under a microscope. This procedure allows you to make the most accurate diagnosis if the disease is associated with the occurrence of neoplasms.

Consequently, the effectiveness of the selected treatment depends on the correct diagnosis. For example, a visually ordinary mole does not cause concern, but it can become malignant at any time, therefore, in order to determine the type of mole and understand what to do with it next, a histological examination is prescribed.

Purpose of prescribing histological examination

Histological examination of neoplasms is prescribed to analyze the dynamics of the growth of a malignant tumor, changes in tissues that occurred after therapy (the effectiveness of treatment is checked), establishing indications for radical surgery, differentiating malignant and benign neoplasms, the presence of a tumor in the early stages of its development, staging the maximum accurate diagnosis.

If the results of the study demonstrate the presence of a pathological process, the doctor selects an effective treatment package in accordance with the diagnosis. It is important to remember that timely diagnosis is the key to successful and short-term treatment, which is possible without surgical intervention.

Two methods are used for research: studying tissues that were obtained during surgery and biopsy (targeted excision of a small piece of tissue for research).

It is important to understand that any wart can be cancer, and a mole can be a malignant tumor, and only histological diagnosis will determine the type of tumor.

Indications and contraindications for the procedure

Among the contraindications it is worth noting:

  • the presence of blood diseases (including poor blood clotting);
  • diabetes;
  • acute viral and infectious diseases;
  • serious central nervous system disorders (congenital or acquired);
  • stage 4 cancer.

It is also necessary to tell your doctor about the presence of drug treatment and allergies to anesthesia.

This type of diagnosis is prescribed if the presence of a tumor has already been established and it is necessary to determine its type and stage, if cosmetic removal of tumors on the skin is necessary, as well as to determine the etiology of tumors, etc. In other words, histological examination of neoplasms makes it possible to establish the diagnosis as accurately as possible. An analysis is also prescribed if there is a suspicion of polyposis. Polyps can form in the body of the uterus, small and large intestines, stomach, nose, and other places where there are mucous membranes.

Algorithm for histology of neoplasms

The first thing you need to do is consult a doctor (,) - the choice of doctor depends on the symptoms. The doctor collects the necessary biological material (aspiration, suction, puncture, collection of secretions from the tumor, mucosal smear).

The resulting biological material is placed in formaldehyde (the solution in volume should be ten times the volume of the material being tested).

The jar with the formaldehyde solution is marked, indicating the patient's data, the date and area of ​​collection of the histological sample. The doctor issues a referral for histology, in which he indicates all the necessary data, including bad habits. On the day of tissue collection, after all documentation has been completed, the excised tissues in formaldehyde solution are transferred to the pathologist. The doctor first stains the obtained samples (special dyes are used), then the process of complete dehydration occurs. After dehydration, the samples are placed in paraffin. The cube of the resulting paraffin is cut into thin slices, which are then placed on glass and examined by a specialist under a powerful microscope.

If no errors were made during the collection of tissues and cells, as well as in the histology algorithm, the results are as accurate as possible and allow you to diagnose the type and stage of the tumor. Taking materials for research will in no way speed up or stop the development of the tumor. A great danger to the human body is the constant traumatization of the neoplasm, as well as late diagnosis.

The average duration of histology of neoplasms after tissue sampling is three days. The doctor may also prescribe an emergency diagnostic test. It is usually prescribed during the operation.

Often the outcome of the operation will depend on the result obtained. Emergency diagnostics do not involve drying samples; they are simply frozen. The patient can receive the results in the form of a conclusion, or they will be transferred directly to the attending physician.

In any case, the attending doctor will decipher the conclusion in order to decide on further actions. Often, after receiving the results, the patient is referred for additional studies. The doctor can also refer you to other specialists in this field.

What can the analysis show?

Histology analysis is not prescribed in all cases. Histology of neoplasms is necessary to determine the inflammatory process in the gastrointestinal tract, to diagnose pathological changes in the female genital organs, to determine the causes of infertility, and to diagnose cancer.

In rare cases, analysis shows false results; according to statistics, 98% of histology shows true results, which makes it possible to establish a diagnosis and determine further actions.