Hexoral instructions for use. Hexoral spray: instructions for use

Content

To prevent diseases of the throat and gums, the antibacterial Hexoral is used - the instructions for use of the medication contain important information about the purpose and dosage. The medicine is an antiseptic (antibiotic) and is available in several forms for convenient use. Read the instructions to be aware of the rules for using the medication.

The drug Hexoral

In ENT practice and dentistry, the drug Hexoral is used, which, according to the pharmacological classification, is an antiseptic. It is intended for topical use, plus Hexoral Tabs tablets are available for oral administration. The active ingredient of the drug is hexetidine. The medicine is suitable for children and adults.

Composition and release form

There are three forms of Hexoral release: spray or aerosol, solution and tablets. The latter do not contain hexethidine. The active ingredient of the tableted antiseptic drug is a mixture of chlorhexidine dihydrochloride and benzocaine, additional components are isomalt, menthol, water, aspartame, thymol and peppermint oil. Tablets are available in 20 pieces per package. Detailed composition of the spray and solution:

Spray Hexoral

Hexethidine concentration, g/100 ml

Additional components of the composition

Citric acid monohydrate, sodium saccharinate, polysorbate, levomenthol, sodium calcium edetate, eucalyptus leaf oil, water, nitrogen, ethanol, sodium hydroxide

Polysorbate, ethanol, anise oil, sodium saccharinate water, azorubine, peppermint oil, citric acid monohydrate, methyl salicylate, levomenthol, eucalyptus and clove oils

Description

Transparent colorless liquid with menthol odor

Clear red liquid with mint flavor

Release format, volume

40 ml bottles with 1 or 4 spray nozzles

200 ml bottles with measuring cup

Pharmacological properties

The drug has an antimicrobial effect due to the suppression of the oxidative process in the metabolism of bacteria. Hexethidine is the opposite active ingredient of thiamine and has a broad effect on bacteria and fungi. Suppresses most strains of pathogens, including the genus Candida and Protea, does not develop resistance to them, and reduces the sensitivity of bacteria.

Effective against influenza A viruses, herpes simplex type 1, and during its action slightly anesthetizes the mucous membranes of the gums. When in contact with the mucous membranes of the oral cavity and pharynx, it adheres well and is practically not absorbed. After a single use, the active substance remains in the gum mucosa for 65 hours, in dental plaque and plaques for 10-14 hours.

Indications for use

Instructions for use indicate the following indications for use of the drug Hexoral:

  • symptomatic treatment of infectious and inflammatory diseases of the oral cavity and pharynx;
  • tonsillitis, pharyngitis;
  • treatment of sore throat, ARVI;
  • gingivitis, stomatitis, glossitis;
  • periodontal disease, fungal infections of the mouth;
  • prevention of infectious complications before and after operations;
  • prevention of infection of the alveoli after tooth extraction, trauma;
  • hygiene and oral diseases (elimination of odor).

Directions for use and dosage

According to the instructions, Hexoral is used for gargling in the form of a solution, and for irrigating the oral cavity in the form of a spray. Hexoral for angina is prescribed in the form of oral tablets. They dissolve in the mouth until completely dissolved. Adults are recommended to take one every 1-2 hours, but no more than 8 per day. Children 4-12 years old can take up to 4 tablets per day. The drug is used immediately after the first symptoms appear, for several days after they disappear.

Hexoral Aerosol

The spray is applied topically and adheres to the oral mucosa, which is reflected in the durability of the effect. The medicine should be used after meals. Adults and children over six years of age treat the mouth while holding their breath, irrigating the mucous membranes once for a couple of seconds twice a day. Children 3-6 years old can use a local antiseptic drug only after consulting a pediatrician. The doctor prescribes the duration of the course depending on the type of disease.

Instructions for use of Hexoral aerosol include the following steps for spraying in the larynx or mouth:

  • put the spray nozzle on the bottle;
  • direct its end to the affected area of ​​the mucous membrane;
  • hold the bottle strictly vertically during administration;
  • spray the required amount of spray by pressing on the head of the spray nozzle;
  • Do not breathe during insertion.

Hexoral solution

The second form of release of Hexoral in the form of a solution is also used topically, after meals. Adults and older children fill the measuring cup to the 15 ml mark, rinse their mouth with an undiluted solution for half a minute, 2-3 times a day. Children 3-6 years old should use the drug only after consulting a doctor. The solution should not be swallowed or diluted with water or other liquids. It is allowed to treat the affected areas of the throat with tampons soaked in the medicine. They are applied for 2-3 minutes. The duration of therapy is determined by the doctor.

special instructions

The instructions for use indicate special instructions when using the antiseptic drug. Pay attention to them:

  • one dose of solution contains 20.3 mg, which in terms of pure substance is 5.15%;
  • the contents of the spray bottle are under pressure, do not open, pierce, or burn the packaging even after it is completely empty;
  • if the medicine has expired, do not pour it into wastewater or throw it outside, tie it in a bag and throw it in a trash container;
  • the antiseptic drug does not affect the speed of psychomotor reactions, can be used while driving cars or dangerous mechanisms;
  • the medicine is prescribed with caution if you are sensitive to acetylsalicylic acid;
  • the solution can only be used when the patient can spit it out after rinsing the cavity.

During pregnancy

According to the instructions, there is no information about undesirable effects after using the antiseptic Hexoral during pregnancy and breastfeeding, but you should consult your doctor before prescribing. If he evaluates the benefit to the mother above the risk to the baby, the drug can be used for its intended purpose. There is no data on the penetration of hexethidine across the placenta or into breast milk.

Hexoral for children

According to the instructions, the medication is contraindicated for use in children under three years of age. Hexoral can be prescribed to children when there is no danger of uncontrolled swallowing or resistance to a foreign object in the mouth (spray nozzle). If the child cannot yet independently hold his breath during injection, it is better not to use the medicine.

Drug interactions

According to the instructions for use of Hexoral, drug interactions of the aerosol and solution with other medications are not described. From this we can conclude that medications can be combined in any order, but before any treatment of infections, medical consultation is necessary. This will help avoid negative effects on the health of the body.

Side effects

Instructions for use of Hexoral indicate the following possible side effects that occur when taking it:

  • allergic reactions, hypersensitivity, urticaria, angioedema;
  • ageusia, dysgeusia, poisoning;
  • cough, shortness of breath;
  • numbness and discoloration of the tongue, short-term loss of taste;
  • dry mouth, nausea, vomiting, increased salivation;
  • irritation of the mucous membrane, burning, paresthesia;
  • inflammation of the mucous membranes, formation of blisters and ulcers;
  • darkening of the enamel color.

Overdose

According to the instructions, it is unlikely that hexethidine has a toxic effect when taken in recommended doses. If the drug is accidentally swallowed, symptoms of alcohol intoxication may appear. Treatment is gastric lavage within two hours after the child swallows the dose, symptomatic therapy. In any case of overdose, the patient should see a doctor.

An overdose of tablets is unlikely; its symptoms are suffocation, tremors of the limbs, vomiting, and convulsions. Respiratory depression can cause coma and death. Treatment consists of artificially inducing vomiting and gastric lavage with activated charcoal. For convulsions, barbiturates or diazepam are prescribed, for hypoxia - artificial respiration and suxamethonium chloride, circulatory support by administering electrolyte solutions.

Contraindications

The instructions for use of Hexoral state the following contraindications that prohibit the use of the medication:

  • erosive-squamous lesions of the oral mucosa;
  • age up to three years for spray and solution, up to four years for tablets;
  • hypersensitivity to the components of the composition or acetylsalicylic acid;
  • with caution during pregnancy and breastfeeding.

Terms of sale and storage

The drug is dispensed from pharmacies without a prescription, stored away from children and light at temperatures up to 25 degrees. The shelf life is three years, but the contents of the spray bottle must be used within six months after opening. The solution is stored for two years.

Analogs

Based on the active substance and the therapeutic effect provided, the following analogues of Hexoral are distinguished in the form of a spray and solution, produced by domestic and foreign companies:

  • Stomatidin;
  • Stopangin;
  • Hexosept;
  • Stomolik;
  • Dentagel;
  • Metroviol;
  • Metrohex;
  • Metrogil Denta;
  • Metrodent;
  • Stomatogel;
  • Candide;
  • Metrozol Denta;
  • Metronidazole Denta.

Geksoral's analogue is cheaper

Not all drug analogues are affordable, but the following drugs in the form of a spray or antiseptic solution can be bought at any pharmacy cheaper than Hexoral:

  • Proposol spray;
  • spray and ointment Tantum Verde;
  • Inhalipt spray;
  • antiseptic solution Miramistin;
  • Lizobact lozenges;
  • medicinal aerosol Stopangin.

Hexoral price

The cost of Hexoral depends on the form of release, the manufacturer and the price category of the pharmacy. Prices on the Internet are cheaper than in traditional pharmacies, but you will have to pay for delivery. Approximate prices for medicine.

Hexoral is an antifungal, deodorizing, enveloping, antiseptic, analgesic and hemostatic drug. Active ingredient: Hexetidine.

An antiseptic whose antimicrobial effect is associated with the suppression of oxidative reactions of bacterial metabolism.

It has a wide spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida. May have an effect in the treatment of infections caused by Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg/ml, the drug inhibits most strains of bacteria. The development of resistance has not previously been observed.

Hexoral has an antiviral effect against influenza A viruses, respiratory syncytial virus (RS virus), and herpes simplex virus type 1, which affects the respiratory tract. Has a weak anesthetic effect on the mucous membrane.

Available in the form of a 0.1% solution and 2% aerosol for topical use.

Indications for use

What does Hexoral help with? According to the instructions, the drug is prescribed in the following cases:

  • inflammatory and infectious diseases of the oral cavity and pharynx;
  • in the complex treatment of severe febrile or purulent diseases of the oral cavity and pharynx, requiring the use of antibiotics and sulfonamides, tonsillitis;
  • tonsillitis (including tonsillitis with damage to the lateral ridges, Plaut-Vincent angina);
  • pharyngitis;
  • gingivitis and bleeding gums;
  • periodontopathies, periodontal diseases and their symptoms;
  • stomatitis, glossitis, aphthous ulcers to prevent superinfections;
  • infection of the alveoli after tooth extraction;
  • fungal infections of the oral cavity and pharynx, especially candidal stomatitis;
  • before and after operations in the oral cavity and pharynx;
  • additional oral hygiene for general diseases;
  • elimination of bad breath, especially in the case of decaying tumors of the oral cavity and pharynx;
  • an aid in the treatment of colds.

Instructions for use of Hexoral, dosage

The drug is applied topically.

When using Hexoral aerosol for adults and children over 3 years of age, a single dose is administered over 1-2 seconds while holding your breath.

When using a topical solution, rinse the mouth and throat with 15 ml of undiluted solution for 30 seconds.

The drug is prescribed 2 times a day (preferably in the morning and evening), after meals. According to the instructions for use, Hexoral is safe even with more frequent use. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals.

The duration of treatment is determined by the doctor.

Correct Application

  1. Place the spray nozzle on the bottle.
  2. Direct the sprayer to the area of ​​the inflammatory pathological process in the pharynx or oral cavity.
  3. When spraying the drug, the bottle must be kept in an upright position.
  4. To spray the aerosol, you need to press the spray nozzle and hold it for several seconds; after spraying, it is recommended to hold your breath for a short period of time.

Long-term use of Hexoral spray is not recommended, as this can lead to disruption of the functioning of taste buds and the development of dysbiosis (death of bacteria representing normal microflora with the subsequent development of opportunistic microorganisms).

Care should be taken not to swallow the aerosol while spraying.

Side effects

The instructions warn about the possibility of developing the following side effects when prescribing Hexoral:

  • allergic reactions of hypersensitivity to the drug;
  • with prolonged use, taste disturbance may occur.

Contraindications

It is contraindicated to prescribe Hexoral in the following cases:

  • children under 3 years of age;
  • hypersensitivity to any of the components of the drug

There is no data on any damaging effects of the drug during pregnancy and lactation. Before prescribing Hexoral to pregnant or lactating women, the doctor must carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placental barrier and into breast milk.

Overdose

Store at a temperature not exceeding +25 °C. Keep away from children. The shelf life of the solution is 2 years, the aerosol is 3 years.

The contents of the aerosol can must be used up within 6 months after opening.

Conditions for dispensing from pharmacies - without a prescription.

In ENT practice, Hexoral spray is used for injection into the throat - the instructions for use of the medication indicate that it eliminates bacteria and relieves gum inflammation. This medicine is indicated for children and adults, provided there are no problems with holding their breath. According to the instructions, you need to hold your breath during insertion to avoid suffocation. Read more about other rules for using the drug below.

According to the pharmacological group, the spray is an antiseptic for topical use. In addition to ENT practice, it is actively used in dentistry to relieve sore throats and treat gum mucosa from bacteria. This antiseptic drug is used to treat infections, sore throats, dry coughs, and can be prescribed to pregnant women (with caution) and to children after reaching three years of age.

Compound

Aerosol for topical use Hexoral is available in the form of a clear, colorless liquid with a menthol odor. Available in 40 ml aluminum cans with one or four spray nozzles, packaged in cardboard boxes. Detailed composition of the medicine:

Substance

Concentration, g/100 ml

Hexethidine (active substance)

Polysorbate

Citric acid monohydrate

Sodium saccharinate

Levomenthol

Eucalyptus leaf oil

Sodium calcium edetate

Sodium hydroxide

Required amount to obtain acidity 5.5

Required quantity to obtain a volume of 100 ml

Required quantity to obtain a pressure of 5 bar

Pharmacodynamics and pharmacokinetics

The antiseptic substance has an antimicrobial effect associated with the suppression of bacterial metabolism and their oxidative reactions. Hexetidine is considered a thiamine antagonist and acts against a wide range of gram-positive bacteria and fungi of the genus Candida. The drug is effective against infections of microorganisms caused by pseudomonas and Proteus. At a concentration of 100 mg/ml, it suppresses most oral pathogens without causing the development of resistance.

The drug Hexoral is capable of killing influenza A viruses, respiratory syncytial virus (causes ARVI), and herpes simplex virus type 1, which affects the respiratory tract. Once on the mucous membrane, hexethidine has a weak anesthetic effect. It is practically not absorbed by the stomach, because it remains on the mucous membrane of the cavity. With a one-time use, traces of the drug can be found in the gums 65 hours after administration; they remain in dental plaque for up to 10-14 hours.

Indications for use

Instructions for use indicate the following indications for prescribing Hexoral antibiotic aerosol to patients:

  • tonsillitis, tonsillitis, including lesions of the lateral ridges and Plaut-Vincent;
  • symptomatic treatment of infectious and inflammatory diseases of the oral cavity, larynx and pharynx;
  • pharyngitis, gingivitis, stomatitis;
  • glossitis, periodontal disease, fungal infections of the oral mucosa and gums;
  • prevention of throat infections and complications before and after pharyngeal surgery;
  • prevention of infection of open areas after tooth extraction;
  • oral hygiene to eliminate unpleasant odor from it.

Directions for use and dosage

Instructions for use of Hexoral spray indicate the step-by-step use of the drug for medicinal purposes:

  • put a spray nozzle on the bottle (use a different nozzle for each family member to prevent re-infection);
  • point the end of the nozzle at the affected area of ​​the pharynx;
  • insert the nozzle, holding the bottle vertically;
  • hold your breath;
  • press the spray head once, spray the spray for a couple of seconds.

The drug is applied topically, adheres to the mucous membranes of the gums, and therefore gives a lasting, effective result. To keep it as long as possible, use the spray after meals. For adults and children over six years of age, treat the throat twice a day, pressing once for a couple of seconds. In children 3-6 years old, the medication can be used for its intended purpose only after consulting a pediatrician.

Hexoral for sore throat

Bacteria, viruses or fungi can cause a sore throat, the symptoms of which include a dry and sore throat, discomfort when swallowing and fever. The consequences of the disease can be inflammation of the tonsils, acute otitis media, abscess and swelling of the larynx. To prevent complications, treatment of sore throat with antiseptics and rinses should begin immediately after the onset of symptoms. You can use Hexoral solution, spray or tablets.

According to research, hexetidine destroys 99% of viruses, 97% of bacteria and 91% of fungi. The spray does not mask inflammation of the throat, the effect of a single use lasts up to 12 hours, so it can be used twice a day after meals. The drug has a mild analgesic and antiseptic effect and is practically not absorbed into the bloodstream. When treating, you first need to gargle and then spray the spray on the larynx.

Hexoral for cough

If a dry cough appears against the background of a cold, laryngitis, or pharyngitis, it is necessary to sanitize the throat and increase the body's defenses. For this it is good to use Hexoral spray. The antiseptic eliminates infection in the throat, inflammation of the mucous membranes of the gums, and has a prolonged effect. You can use it twice a day by pressing the sprayer once. A spray is unlikely to help with a wet cough; expectorant medications are needed.

special instructions

There are no special instructions for the use of the spray, but the instructions contain a special instructions section. Excerpts from it will help in the correct use of the drug:

  • the contents of the cylinders are under pressure, therefore it is strictly prohibited to pierce, burn or disassemble even empty packages;
  • the medication contains ethanol in the amount of 5.15%, which in terms of absolute alcohol is 20.3 mg;
  • If the product has expired or has become unusable for any other reason, do not pour the remaining product into waste water or onto the street: to protect the environment, place the packaging in a bag, wrap it and place it in a waste container;
  • the use of an aerosol does not affect the concentration of attention and the speed of psychomotor reactions, so it can be used when driving a car or performing potentially dangerous activities.

During pregnancy

The instructions warn that there is no information about the negative effects on the fetus during pregnancy or the newborn when breastfed by a mother using Hexoral spray. There is also no information about the penetration of hexethidine through the placental barrier and into breast milk. Before prescribing, consult your doctor so that he can evaluate the benefit to the mother outweighs the risk to the child's development.

Hexoral spray for children

According to the instructions, children can use the drug in a spray from an age when there is no danger of uncontrolled swallowing or resistance to a foreign object in the mouth (spray nozzle). The child should be able to hold his breath when injecting. Hexoral spray is contraindicated for children under the age of three years. Children from three to six cannot be treated with the drug without receiving a prescription from a pediatrician.

Drug interactions

The instructions do not describe the drug interactions of Hexoral with other medications, so it is unlikely that negative reactions will occur when combined with the spray. Before treatment with any combination of drugs, you should consult a doctor to minimize the risks and prevent possible negative effects on the health of the body.

Side effects and overdose

Instructions for use of Hexoral spray indicate the possible occurrence of the following side effects:

  • hypersensitivity reaction, allergy, urticaria, angioedema;
  • ageusia, dysgeusia;
  • loss of taste;
  • cough, shortness of breath, dry mouth;
  • dysphagia, nausea, enlarged salivary glands, vomiting;
  • irritation of the oral mucosa, burning sensation;
  • paresthesia of the oral cavity, discoloration of teeth and tongue;
  • inflammation of the cavity, formation of blisters and ulcers at the site of application.

If side effects from Hexoral spray develop rapidly, you should consult a doctor. According to the instructions, an overdose of the drug is unlikely, because the toxic effect does not occur in small and recommended doses. If a large amount of the spray is accidentally swallowed, symptoms of alcohol intoxication may appear because the dose of ethanol is large. Treatment consists of gastric lavage within two hours after the incident, followed by symptomatic therapy, as with alcohol poisoning.

Contraindications

The instructions for use of Hexoral spray indicate the following contraindications for which the use of the drug for its intended purpose is strictly prohibited:

  • erosion, damage to the mucous membrane of the oral cavity and pharynx, damage;
  • age up to three years;
  • hypersensitivity to the components of the composition;
  • with caution during pregnancy and lactation.

Terms of sale and storage

Pharmacies sell Hexoral without requiring a prescription from the patient. The container with liquid is stored out of the reach of children, protected from light, at an air temperature of up to 25 degrees. The shelf life is three years, but after opening it is recommended to store the medicine for only six months.

Analogue of Hexoral

If the spray is not suitable due to side effects in the treatment of inflammation or cost, pay attention to its analogues. They are produced by domestic and foreign factories, are cheaper than Hexoral, have a similar composition or with the addition of other active substances:

  • Stomatidin;
  • Stopangin;
  • Hexosept;
  • Stomolik;
  • Metroviol;
  • Metrohex;
  • Ambassador;
  • Tantum Verde;
  • Inhalipt.

Price for Hexoral spray

The range of prices for Hexoral spray depends on the level of trade markup of the network in which it is sold and the number of attached nozzles. The cost varies on the Internet and in regular pharmacy departments. Approximate prices for the spray are listed below.

Hexoral: instructions for use and reviews

Latin name: Hexoral

ATX code: A01AB12

Active substance: hexetidine

Manufacturer: McNeil Manufacturing (France), Famar Orleans (France), Johnson & Johnson (Russia)

Updating the description and photo: 16.08.2019

Hexoral is a local antiseptic drug used in dentistry and ENT practice.

Release form and composition

Hexoral is available in the following dosage forms:

  • Aerosol (spray) for topical use 0.2%: transparent colorless liquid with a menthol odor (40 ml in aluminum aerosol cans, 1 can in a cardboard box complete with a spray nozzle);
  • Solution for topical use 0.1%: red transparent liquid with the smell of mint (200 ml in glass bottles, 1 bottle in a cardboard box).

The composition of 100 ml of aerosol includes:

  • Active substance: hexetidine – 200 mg;
  • Auxiliary components: polysorbate 80 – 1400 mg; citric acid monohydrate – 70 mg; sodium saccharinate – 40 mg; levomenthol – 70 mg; Eucalyptus leaf oil – 1.1 mg; sodium calcium edetate – 100 mg; 96% ethanol – 4333 mg; sodium hydroxide – up to pH 5.5±0.2; purified water – up to 100 ml; nitrogen – up to 5 bar.

The composition of 100 ml of solution includes:

  • Active substance: hexetidine – 100 mg;
  • Excipients: 96% ethanol (4330 mg/100 ml solution), 85% azorubine (E122), polysorbate 60, peppermint oil, citric acid monohydrate, anise oil, sodium saccharin, methyl salicylate, levomenthol, eucalyptus oil, clove oil, purified water.

Pharmacological properties

Pharmacodynamics

The antimicrobial effect of hexethidine is due to inhibition of the oxidative reactions of the metabolism of bacterial microorganisms. Also, the active component of the drug is a thiamine antagonist and is characterized by a wide spectrum of antifungal and antibacterial action, including Candida fungi and gram-positive bacteria. However, in some cases Hexoral can also be used to treat infectious diseases caused by Proteus spp. or Pseudomonas aeruginosa. At a concentration of 100 mg/ml, hexetidine inhibits most bacterial strains, and resistance to the drug practically does not develop. The substance has a slight anesthetic effect on the mucous membrane.

Hexoral is characterized by an antiviral effect against influenza A viruses, herpes simplex virus type 1, and respiratory syncytial virus (RS virus), which affects the respiratory tract.

Pharmacokinetics

Hexethidine has a high degree of adhesion to the mucous membrane and is almost not absorbed.

After a single use of Hexoral, its trace concentrations are detected on the gum mucosa for 65 hours. In dental plaque, active concentrations are determined within 10–14 hours after application.

Indications for use

  • Infectious and inflammatory diseases of the oral cavity and pharynx;
  • Bleeding gums and gingivitis;
  • Angina (including Plaut-Vincent's tonsillitis, tonsillitis with damage to the lateral ridges);
  • Pharyngitis;
  • Periodontopathies;
  • Infection of the alveoli after tooth extraction;
  • Fungal infections of the pharynx and mouth, especially candidal stomatitis;
  • Severe febrile or purulent diseases of the pharynx and mouth, requiring the use of antibiotics and sulfonamides, tonsillitis;
  • Glossitis, stomatitis, aphthous ulcers (for the prevention of superinfections).

According to the instructions, Hexoral is also used before and after operations in the oral cavity and pharynx as an additional oral hygiene product for general diseases, to eliminate bad breath, especially with collapsing tumors of the pharynx and oral cavity, and as an auxiliary drug during the treatment of colds .

Contraindications

  • Age up to 3 years;
  • Hypersensitivity to the components of the drug.

Before prescribing Hexoral, nursing and pregnant women need to carefully weigh the risks and expected benefits of treatment (taking into account the lack of sufficient data on excretion in breast milk and penetration of the drug through the placental barrier).

Instructions for use of Hexoral: method and dosage

Hexoral is prescribed to adults and children over 3 years of age. If there are no other instructions from the doctor, the drug is used 2 times a day after meals, preferably in the morning and evening. Hexoral is also considered safe with more frequent use.

The duration of therapy is determined by the doctor.

Hexoral spray is used topically as a spray in the pharynx and mouth. A single dose should be sprayed for 1-2 seconds.

Due to the fact that the active substance of the drug adheres to the mucous membrane, Hexoral gives a lasting effect.

To use, you need to put the spray nozzle on the aerosol can and point its end at the affected area of ​​the pharynx or mouth. During the administration of Hexoral, the bottle must be kept in an upright position at all times. During the procedure (1-2 seconds) you should not breathe.

The drug in the form of a solution is used topically. Rinse the pharynx and mouth with 15 ml of undiluted solution for at least 30 seconds. The solution should not be swallowed.

When rinsing, you should always use an undiluted solution. When treating diseases of the oral cavity, Hexoral can also be applied using a tampon.

Side effects

In some cases, hypersensitivity reactions may occur during therapy.

With prolonged use of Hexoral solution or spray, taste disturbance may occur.

Overdose

When used in accordance with the instructions, it is considered unlikely that hexethidine may have a toxic effect on the body. Ingestion of Hexoral in large quantities sometimes leads to the appearance of symptoms/signs of alcohol intoxication, since the drug contains ethanol.

At the slightest suspicion of an overdose, you should consult a specialist. Typically, in this case, symptomatic treatment is prescribed, as with alcohol intoxication. After swallowing Hexoral in large doses, gastric lavage must be performed within 2 hours.

special instructions

In children, Hexoral can be used from an age when they do not resist a foreign object in the mouth (spray nozzle) when using an aerosol and can hold their breath when injecting the drug, or when there is no danger of uncontrolled swallowing of the solution.

Impact on the ability to drive vehicles and complex mechanisms

Hexoral does not affect the ability to drive vehicles and perform potentially dangerous types of work that require increased concentration and immediate psychomotor reactions.

Use in childhood

For children, Hexoral in both dosage forms is contraindicated under the age of 3 years.

Drug interactions

There is no information on interactions with other drugs.

Analogs

Analogs of Hexoral are: Hexosept, Hexetidine, Stopangin, Stomatidin, Ingalipt.

Terms and conditions of storage

Store out of the reach of children at a temperature:

  • Aerosol – up to 30 °C;
  • Solution – up to 25 °C.

Shelf life – 2 years.

Hexoral in aerosol form can be used for 6 months after the first use.

A local antiseptic medicine is Hexoral. Instructions for use indicate that spray or aerosol 0.2%, solution 0.1%, Tabs tablets are prescribed in dentistry and ENT practice. According to doctors, this drug helps in the treatment of sore throat, pharyngitis and gingivitis.

Release form and composition

The drug is available in the following dosage forms:

  • Aerosol for topical use 0.2% (sometimes mistakenly called a spray).
  • Lozenges Geksoral tabs.
  • Solution for topical use 0.1%. The composition of the medicine in the form of a solution includes the active component hexethidine (100 mg).

Hexoral spray is contained in a 40 ml aluminum bottle. The cardboard pack contains one bottle of solution, a spray nozzle and instructions for using the drug.

The composition of the medicine in the form of an aerosol includes the active component hexetidine (200 mg), as well as additional components: polysorbate 80, citric acid monohydrate, levomenthol, sodium saccharinate, sodium calcium edetate, eucalyptus leaf oil, sodium hydroxide, water.

Indications for use

What does Hexoral help with? Spray and solution are used in the following cases:

  • for periodontopathies;
  • to ensure additional oral hygiene for common diseases;
  • for gingivitis and bleeding gums;
  • in case of infection of the alveoli after the tooth has been removed;
  • for infectious inflammatory diseases of the pharynx and oral cavity;
  • with sore throat;
  • with tonsillitis;
  • to eliminate bad breath, in particular in people with disintegrating tumors of the pharynx and oral cavity;
  • with pharyngitis;
  • in the period before and after operations of the pharynx and oral cavity;
  • for candidal stomatitis, as well as a number of other fungal infections of the pharynx and oral cavity;
  • in the complex treatment of severe febrile or purulent diseases of the pharynx and oral cavity and pharynx, for which antibiotics and sulfonamides are prescribed;
  • for aphthous ulcers, glossitis, stomatitis, as well as for the prevention of superinfections;
  • as an auxiliary drug in the treatment of colds.

Instructions for use

Hexoral is applied topically. When using an aerosol for topical use in adults and children over 3 years of age, a single dose is administered over 1-2 seconds. When using a solution for topical use, rinse the mouth and throat with 15 ml of undiluted solution for 30 seconds.

The drug is prescribed 2 times a day (preferably in the morning and evening), after meals. Safe with more frequent use. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals. The duration of treatment is determined by the doctor.

Rules for using the drug

When using a topical aerosol, the drug is sprayed into the mouth or throat. Using an aerosol you can easily and quickly treat the affected areas. You need to do the following:

  1. Place the aerosol tube in the corresponding hole in the upper part of the bottle, lightly pressing on it, and point the tip of the tube away from you.
  2. Hold the aerosol tube and direct it to the affected area of ​​the mouth or pharynx.
  3. During administration, the bottle should be kept in an upright position at all times.
  4. Inject the required amount of the drug by pressing on the head for 1-2 s, do not breathe while administering the aerosol.

The topical solution can only be used to rinse the mouth and throat. The solution should not be swallowed. When rinsing, you should always use an undiluted solution. When treating diseases of the oral cavity, the solution can also be applied using a tampon.

Pills

The tablet should be slowly dissolved in the mouth until completely dissolved. The drug should be started immediately after the first symptoms of the disease appear and continued for several days after the symptoms disappear.

Adults and children over 12 years of age are prescribed 1 tablet every 1-2 hours as needed, but not more than 8 tablets per day. Children aged 4-12 years are prescribed up to 4 tablets per day.

pharmachologic effect

The antimicrobial effect of hexethidine is due to inhibition of the oxidative reactions of the metabolism of bacterial microorganisms. Also, the active component of the drug is a thiamine antagonist and is characterized by a wide spectrum of antifungal and antibacterial action, including Candida fungi and gram-positive bacteria.

In some cases, Hexoral can also be used to treat infectious diseases caused by Proteus spp. or Pseudomonas aeruginosa. At a concentration of 100 mg/ml, hexetidine inhibits most bacterial strains, and resistance to the drug practically does not develop.

The substance has a slight anesthetic effect on the mucous membrane. Hexoral is characterized by an antiviral effect against influenza A viruses, herpes simplex virus type 1, and respiratory syncytial virus (RS virus), which affects the respiratory tract.

Contraindications

An absolute contraindication to the use of Hexoral spray is the presence of individual intolerance, hypersensitivity to the active substance or auxiliary components of the drug. It should also not be used by children under 3 years of age.

Side effects

In some cases, hypersensitivity reactions may occur during therapy. With prolonged use of Hexoral solution or spray, taste disturbance may occur.

Children, pregnancy and breastfeeding

It should be borne in mind that this drug can be prescribed to children after reaching three years of age. The instructions for children inform that the use of the solution is possible at an age when the child is able to consciously rinse the mouth and throat, and there is no danger of swallowing the liquid.

Hexoral spray is also not used for children under 3 years of age. It is important that the child does not resist the spray nozzle in the mouth and can hold his breath while the drug is injected.

For children over 3 years of age, the product is used in the dosage indicated in the instructions.

There is no data on any damaging effects of the drug Hexoral during pregnancy and lactation. However, before prescribing a medication to pregnant or lactating women, the doctor must carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placental barrier and into breast milk.

special instructions

Before you start using the drug, you must carefully read the instructions for it; there are several special instructions that are important to consider:

It is better to spray after eating, after rinsing your mouth with water; after treating the oral cavity, it is advisable not to eat or drink for an hour. Care should be taken not to swallow the aerosol while spraying. It is not recommended to drink alcohol during treatment.

Long-term use of Hexoral spray is not recommended, as this can lead to disruption of the functioning of taste buds and the development of dysbiosis (death of bacteria representing normal microflora with the subsequent development of opportunistic microorganisms).

Hexoral spray does not affect the speed of psychomotor reactions and concentration, however, it is worth considering that this is an alcohol-containing drug, so if a large amount of the aerosol is used or it gets into the stomach, the effect of mild intoxication may develop.

Drug interactions

Benzocaine, due to the formation of its metabolite 4-aminobenzoic acid, reduces the antibacterial activity of sulfonamides and aminosalicylates. Sucrose, polysorbate 80, insoluble salts of magnesium, zinc and calcium reduce the effect of chlorhexidine.

Analogues of the drug Geksoral

Analogues are determined by structure:

  1. Stomatidin.
  2. Maxisspray.
  3. Stopangin.
  4. Hexosept.
  5. Hexethidine.

Which is better: or Hexoral?

In general, the effects of these drugs on the body are similar. But Inhalipt is prescribed for a narrower range of diseases. Inhalipt is several times cheaper than Hexoral.

Vacation conditions and price

The average cost of Hexoral (40 ml aerosol) in Moscow is 307 rubles. The price of Hexoral Tabs tablets is 174 rubles for 20 pieces. The drug is available in the pharmacy chain without a prescription. If you have any questions or doubts regarding its use, you should consult your doctor.

The shelf life of the drug is 2 years from the date of manufacture. The spray must be stored out of the reach of children at a temperature not exceeding +25 C; it should not be allowed to freeze. Hexoral in aerosol form can be used for 6 months after the first use.

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