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The drug Grammidin is a local antiseptic intended for the treatment and relief of symptoms of inflammation in the mouth and pharynx. It is often used to combat seasonal colds and dental problems. High efficiency, ease of use and affordable price have made Grammidin lozenges one of the people's most favorite remedies for sore throats. Today we will tell you in detail about the composition of this drug, its correct use and possible contraindications.

Pharmacological action and composition of Grammidin

The name of the Grammidin brand is consonant with the main active component of this drug - the antibiotic gramicidin C. It has a very wide spectrum of bactericidal action, and quickly copes with almost any microbes that infect the oral cavity and pharynx of a person. This antibiotic is often used not only by therapists and pediatricians, but also by dentists.

Resorption of the tablets promotes abundant salivation, and thanks to this, the antibiotic quickly and evenly spreads throughout the oropharynx. Saliva helps to wash away microbial waste products, which is also important for a speedy recovery. Grammidin weakens the cell membrane of bacteria, and they quickly die. And several medicinal forms of the drug make its use as convenient as possible.

Release form Grammidin

The drug is available in three forms:

Grammidin is a yellowish-white suckable tablet, each containing 1.5 mg of the antibiotic gramicidin C, as well as a number of excipients (lactose, sugar, methylcellulose, calcium stearate). The tablets are in blisters of 10 pieces, each cardboard package contains two blisters;

Grammidin Neo are convex-shaped suckable tablets with menthol flavor, with the inscription “GR” on one side. In addition to the antibiotic gramicidin in a dosage of 3 mg, they added another active substance - cetylpyridinium chloride. This component softens the pain in the sore throat that occurs when swallowing. Excipients Grammidin Neo: silicon dioxide, potassium acesulfate, magnesium stearate, menthol, sorbitol and talc. The drug is available in blisters of 6 or 9 pieces, which are packed in cardboard boxes of 4 or 2 blisters, respectively;

Grammidin with anesthetic - convex-shaped suckable tablets with lemon, black or lemon flavor. Here, to 1.5 mg of the antibiotic gramicidin, 10 mg of the anesthetic lidocaine is added, which perfectly relieves acute sore throat with sore throat. Excipients: eucalyptus oil, citric acid, hydroxypropylcellulose, menthol, aspartame, mannitol and fruit flavor. The tablets are packaged in the same way as Grammidin Neo.

Indications and contraindications for use

Drugs from the Grammidin series are prescribed for the treatment of the following inflammatory diseases:

If the disease is accompanied by acute pain, it is better to take Grammidin with an anesthetic. As for contraindications, there are none - the drug is prescribed with caution during pregnancy. It is contraindicated for nursing mothers.

How to take Grammidin

Adult patients are prescribed two Grammidin tablets 4 times a day or one Grammidin Neo tablet 4 times a day for one week. You need to dissolve first one and then immediately a second tablet, and it is better not to do this on an empty stomach, since after taking the drug you cannot eat or drink for two hours. The slower the process of resorption of the tablets occurs, the better the therapeutic effect. Grammidin with an anesthetic can be taken more often during the treatment of severe, painful sore throat, but it is still not recommended to dissolve more than six tablets per day. Children aged four to twelve years are prescribed one tablet of regular Grammidin (dosage 1.5 mg) three times a day.

Conditions of release and storage

The drug can be freely purchased at any pharmacy without a doctor's prescription, but this should not be done. There are known precedents for allergic reactions to both the active and auxiliary components of Grammidin. Your attending physician, based on data from all previous cases of drug allergies in you or your child, will be able to give a competent recommendation on the choice of antiseptic to treat a sore throat.

Grammidin is stored in a dry, cool and dark place for no more than 2 years from the date of manufacture, which is indicated on the cardboard packaging.

Official instructions

About the doctor: From 2010 to 2016 practicing physician at the therapeutic hospital of the central medical unit No. 21, the city of Elektrostal. Since 2016 he has been working at diagnostic center No. 3.

The drug Grammidin is a combination drug for the treatment of diseases of the oropharynx with infectious etiology. Available in the form of lozenges. There are several forms of medication. There are regular Grammidin, separately for children and with the addition of an anesthetic. Available without a prescription. The duration of drug therapy is no more than 14 days.

Compound

Instructions for use of Grammidin contain information about the composition of the drug. It includes:

• active ingredient gramicidin C;
• cetylpyridinium chloride;
• auxiliary connections.

The active component belongs to the group of antibiotics. Belongs to a number of tyrothricine substances. Has a wide spectrum of action. Affects staphylococcus and streptococcus, which are often the causes of inflammation. Basically, it exhibits greater activity against a group of gram-positive microorganisms.

Long-term use does not cause the development of resistance.

Cytylpyridinium chloride belongs to the group with an antiseptic effect. Affects the growth and development of pathogenic microbes. During resorption, increased salivation occurs. This helps to quickly cleanse the oral cavity of pathogenic flora.

Grammidin tablets with anesthetic additionally contain oxybuprocaine, which has a pronounced analgesic effect: the sensitivity of the nerves decreases, and the sensation of sore throat decreases. The combined action of an anesthetic and antibacterial compound ensures a rapid treatment effect.

Auxiliary components include:

• silicon dioxide in small quantities;
• talc substance;
• mint sweetener;
• sorbitol;
• magnesium stearate.

They do not affect the disease in any way.

Action

Grammidin tablets help against all infectious pathologies of the oropharynx. This happens due to its antimicrobial and antiseptic action. A drug with an active antibiotic in its composition reduces the activity and growth of microbes, this is achieved through the formation of a bactericidal and bacteriostatic effect. Accordingly, the death of a certain type of microbe occurs.

Grammidin C affects the synthesis of proteins in the cellular structure. Glycoprotein inhibition occurs. This is the main protein in the cell that is responsible for its growth. For this reason, lysis of the microbial cell develops.

Thanks to this effect, inflammation decreases and symptoms subside. Grammidin with an anesthetic also has an analgesic effect. If you have a severe sore throat, you should use this type of medicine. The drug is effective for diseases of the pharynx with a microbial nature.

In addition to the main effect, an antiseptic effect is added. Taking Grammidin provides a complex effect on pathogens of oropharyngeal diseases. Their activity decreases, their growth and development slows down.

Due to this, signs of inflammation are reduced. The pain in the throat subsides and the tickling sensation disappears. If there is no improvement with the use of the medicine, you should consult a doctor.

What is it produced in and how is it stored?

Available in the form of throat tablets with a scarf on the package. The following types of Grammidin are distinguished:

• ordinary;
• with anesthetic;
• children's

There are 6 pieces on the blister. One package contains 3 such blisters. The green color of the packaging indicates regular Grammidin. If there is a red scarf on the container, it means it contains anesthetic tablets. For children, a package with a yellow scarf. The tablets themselves are white and sweet.

Dispensed from a pharmacy without a prescription. They should be stored in a dry place out of reach of children. Do not store the packaging in direct sunlight or at temperatures above 25 degrees. Shelf life: no more than 2 years. It is indicated on the packaging. After expiration, do not use.

In what cases is Grammidin used?

The medicine Grammidin is prescribed for pathology of the oropharyngeal cavity. Indications for use are as follows:

• angina;
• laryngitis or pharyngitis;
• stomatitis, inflammation of the gums (gingivitis);
• chronic tonsillitis.

Sore throat is a disease caused by pathogenic flora in the oral cavity. Since Grammidin has a bactericidal, antiseptic and analgesic effect, it is prescribed for sore throat. The effect is formed from the first dose.

It is important that throat tablets with Grammidin must be dissolved slowly. Due to this, the action will last longer.

You can use Grammidin for a cough if the cause of the cough is an infectious process in the oropharynx. In general, this medicine does not have an antitussive effect..

Indications for the use of children's Grammidin are similar. But it is only allowed from 4 years old.

How is it distributed in the body?

According to the annotation for the medicine, its use does not affect the general condition of the body. Has only local effect. This means that it is almost not absorbed into the systemic circulation. With prolonged use, a small proportion of the active substance may enter the bloodstream. In this case, it is excreted through the renal system from the body.

Contraindications

There are a number of contraindications to the use of Grammidin. These include:

• individual intolerance to the main components of the drug;
• development of allergies;
• first trimester of pregnancy;
• children under 4 years of age.

Intolerance to the main components can occur in the form of an allergic reaction on the skin or oral mucosa. You should pay attention to the formation of redness on the mucous membrane in the oral cavity. Itching and red spots may occur on the skin. Allergies develop both to the first use and to subsequent uses.

Grammidin is not recommended for use during lactation. When used topically, a small portion may enter the bloodstream. Then the active substance is filtered through the vessels into milk. You should not use the drug yourself without a doctor's recommendation.

Interaction with other drugs

Simultaneous use with other antibacterial drugs enhances their effect. This group includes substances for both local and systemic use.

Methods of administration

According to RLS, Grammdin should be prescribed only for local therapy. The drug should not be taken orally. The tablets should be dissolved slowly after meals, not chewed. After use, do not drink or eat food for 1 hour. This will allow the active substance to have a therapeutic effect.

For children over 12 years of age and all adults, take 1 tablet, no more than 6 tablets per day. It is better to keep the medicine under the tongue during resorption.. This will allow the medication to dissolve faster.

For children aged 4 to 12 years, the maximum daily dose is no more than 3 tablets. The duration of therapy is a week. If the drug does not help within 7 days, you should tell your doctor.

Undesirable effects and overdose

Side effects occur with long-term use. The development of allergies to the first and subsequent doses is noted. In this case, you should stop using the substance.

Long-term use may cause gastrointestinal problems. Especially in people with chronic gastrointestinal diseases. Nausea and heartburn occur. In rare cases, vomiting is observed.

In addition to the effect on the gastrointestinal tract, a feeling of numbness in the oral cavity may form. But this happens in rare cases. This complication is caused by Grammidin with an anesthetic.

Due to low absorption, systemic side effects are rare.

Long-term use may cause the following effects:

• from the gastrointestinal tract, severe nausea followed by vomiting;
• diarrhea occurs.

If such symptoms appear, you should stop taking it.

According to the instructions, it should not be used if there are open surfaces in the oral cavity. This is due to the fact that the drug slows down the regeneration processes in the wound. Does not affect the ability to use the vehicle. There are no special instructions for people working with high concentration levels. Available only in tablet form. There is no spray form with Grammidin.

Contraindicated for phenylketonuria, as it contains aspartame.

Used both for monotherapy and in combination with other medicinal substances.

The price of Grammidin depends on its type. In general, the cost ranges from 300 rubles. One package may not always be enough for a course of throat treatment.

In case of severe pain, Grammidin should be used with an anesthetic.

Gramicidin S. This component has an antimicrobial effect, which helps restore the normal state of the mucous membranes. Bactericidal is aimed at combating gram-positive and gram-negative bacteria, which are the causative agents of infectious diseases of the oral cavity. The drug increases the permeability of microbial cell membranes, which leads to their death.

When using this product, salivation significantly increases, which contributes to the effective cleansing of the oral cavity from infection-causing bacteria and their metabolic products. The anesthetic dosage form contains lidocaine and menthol, which eliminate pain and make swallowing easier. The anesthetic acts within 30-40 minutes. The drug enhances the effect of other antibiotics.

The drug "Grammidin" is available in the form of lozenges.

Indications for use

The drug is prescribed for the treatment of infectious and inflammatory diseases of the oral cavity. In particular, "Grammidin" is used to treat tonsillitis and acute pharyngitis. The drug is also prescribed for the treatment of gingivitis and periodontal disease. In case of pain, to alleviate the condition, it is recommended to take “Grammidin” with an anesthetic.

Instructions for use

The drug is taken 4 times a day, the duration of treatment with Grammidin is 5-6 days. Adults and children over 12 years old take 2 tablets per dose, children under 12 years old - 1-2 tablets. "Grammidin" with an anesthetic is taken in the same dosage.

The tablet must be placed on the tongue and kept in the mouth until completely dissolved, without chewing. If you take 2 Grammidin tablets at a time, you must take the first tablet, then wait 20-30 minutes and take the second tablet in the same way.

After taking the drug, you should not eat or drink for 1-2 hours.

Contraindications and side effects

The drug "Grammidin" is contraindicated in the presence of allergic reactions to its components. During lactation and the first trimester of pregnancy, taking the drug is prohibited; in the second and third trimester it is not recommended. If there is an urgent need to take the drug during lactation, you should refrain from feeding. "Grammidin" with an anesthetic is not prescribed to children under 4 years of age.

As a rule, treatment occurs without side effects. In rare cases, the drug may cause allergic reactions or short-term loss of sensation in the tongue.

A medicine belonging to the group of antibiotics and antiseptics is Grammidin. Instructions for use indicate that lozenges with Neo anesthetic and antibiotic are prescribed for the treatment of infectious and inflammatory pathologies of the mouth and throat.

Release form and composition

The drug Grammidin is available in the form of lozenges. One tablet contains 1.5 mg (1500 units of action) grammidin C as the main active ingredient. It also contains auxiliary components.

• Grammidin lozenges (for children) are packaged in blister packs of 6 pieces. The cardboard pack contains 3 blister packs (18 tablets) and instructions for use of the drug.
• Grammidin NEO. White, round, biconvex tablets with “GR” printed on one side. Each tablet contains 3 mg of Gramicidin C and 1 mg of cetylpyridinium chloride.
• Grammidin with anesthetic. Round, biconvex tablets with a menthol odor. Each tablet contains 1.5 mg Gramicidin C, 10 mg lidocaine hydrochloride and excipients. The drug is supplemented with flavorings (raspberry - white-pink tablets and raspberry flavor, lemon - white-yellow color and lemon flavor or blackcurrant - white-gray color and blackcurrant flavor) or without them - white-cream tablets with inclusions.

They also produce Grammidin spray for topical use at 0.06 mg + 0.1 mg per dose. The bottle contains 112 doses. Active substances:

• Cetylpyridinium chloride - 0.10 mg.
• Gramicidin C dihydrochloride - 0.0638 mg (in terms of gramicidin C - 0.06 mg).

The spray also contains Ethanol 96% - 19.00 mg.

pharmachologic effect

The main component, gramicidin C, has a pronounced antimicrobial effect against the most common pathogens of infectious diseases of the pharynx and oral cavity. The drug effectively fights harmful microorganisms, reduces inflammation, facilitates swallowing and alleviates discomfort in the throat.

The anesthetic included in Grammidin has a local anesthetic effect and effectively eliminates pain in the pharynx and oral mucosa. The product relieves pain quite quickly: relief can be felt almost immediately after the tablet is completely absorbed.

Indications for use

What does Grammidin help with? Tablets and spray are prescribed:

• stomatitis (inflammation of the oral mucosa) and other infectious and inflammatory processes in the mouth or throat;
• acute pharyngitis (inflammation of the pharyngeal mucosa);
• periodontitis and gingivitis (inflammation of the gums, periodontal junction, periodontitis);
• acute tonsillitis (tonsillitis).

Instructions for use

Grammidin (including the form with an anesthetic) is prescribed:

• adults and children over 12 years old, 1 tablet 3-4 times a day;
• children aged 4 to 12 years - 1 tablet 1-2 times a day.

The tablets are used after meals, dissolving in the mouth without chewing. Immediately after using the drug, you should refrain from eating and drinking for 1-2 hours. If there is no therapeutic effect within 7 days of taking the drug, the patient should consult a doctor.

Grammidin NEO is prescribed for adults and children (from 12 years old) 1 tablet 3-4 times a day, and for children from 4 to 12 years old - 1 tablet 1-2 times a day. Course duration – 7 days.

Instructions and use of the spray

Locally, by spraying onto the mucous membrane of the mouth and throat. Used after meals.

Dosage for adults: 4 injections per application 3 times a day for 7 days. Immediately after using the drug, you should refrain from eating and drinking for 1 hour.

Contraindications

Resorption of Grammidin tablets (for children) is contraindicated in several physiological and pathological conditions of the body, which include:

• The period of lactation and breastfeeding in women.
• Individual intolerance, hypersensitivity to the active substance or auxiliary components of the drug.
• Children under 4 years of age, which is associated with a high risk of swallowing the tablet or getting it into the respiratory tract during absorption by a young child.

Before starting to use the drug, you must ensure that there are no contraindications.

Side effects

Grammidin throat tablets can cause an allergic reaction in the form of skin rash, hives, and dry mouth.

Children, pregnancy and breastfeeding

The drug is contraindicated for use in the 1st trimester of pregnancy. If it is necessary to use the drug during lactation, the issue of stopping breastfeeding should be decided.

Contraindicated in children under 4 years of age. Children aged 4 to 12 years - 1 tablet 1-2 times a day.

special instructions

Before you start using the drug, you must carefully read the instructions for it. There are several special instructions that you should pay attention to:

The use of Grammidin tablets enhances the therapeutic effect of other antibacterial drugs, so their combined use is often recommended.

The drug contains sugar as an auxiliary component; this should be taken into account by persons with concomitant diabetes mellitus.

It is possible to use the drug for pregnant women, but with caution and if the expected benefit to the mother outweighs the potential danger to the fetus.

The use of the drug does not affect the speed of psychomotor reactions and concentration.

Drug interactions

Gramicidin C can enhance the effect of other antimicrobial drugs.

Before carrying out complex therapy, you should consult with your doctor.

Analogues of the drug Grammidin

Analogues are determined by structure:

1. Gramicidin C (hydrochloride).
2. Grammidin Neo (with anesthetic).

For the treatment of tonsillitis and tonsillitis, analogues of action are prescribed:

Vacation conditions and price

The average cost of Grammidin for children (lozenges No. 18) in Moscow is 307 rubles. The price of NEO tablets with anesthetic is 296 rubles for 18 pieces. Grammidin spray for topical use 0.06 mg+0.1 mg/dose 112 doses - 368 rubles.

In the pharmacy chain, Grammidin lozenges are available without a prescription. If you have any doubts or questions regarding their use, you should consult your doctor.

The shelf life of Grammidin lozenges for children is 2 years from the date of their manufacture. The drug must be stored in a dark place, out of reach of children, at an air temperature no higher than +25 C.

This packaging “in a red scarf” is familiar to many. The drug is often prescribed by pediatricians and general practitioners for bacterial infections of the mouth and throat. Lozenges help to quickly cope with the symptoms of the disease, relieve pain and restore the ability to speak. In this case, the scarf can be green (the usual remedy) and yellow for children. Why does the medicine relieve a sore throat and relieve symptoms of infection?

The main component of the drug is the antibacterial compound gramicidin, which effectively destroys pathogenic bacteria. Depending on the ingredient composition of the medication produced by the Russian pharmaceutical company Valenta Pharmaceuticals ®, there are three forms of antibiotic tablets:

• Grammidin Neo ® (with a special antiseptic component);
• The same remedy, but with an anesthetic;
• Grammidin ® for children with a reduced concentration of gramicidin.

Each has its own characteristics and unique composition, which allows you to choose the optimal treatment regimen.

Grammidin ® - an antibiotic or not?

Yes, it's an antibiotic. The main active ingredient is gramicidin C, an antibacterial agent for topical use, discovered back in the forties of the last century.

The compound produced by the bacteria Bacillus brevis has been refined over several decades and has finally found application - local antibiotic therapy for respiratory infections (oral lozenges).

Gramicidin is active against a wide range of pathogenic microbes: staphylococci, streptococci, some anaerobes. The main area of ​​its bactericidal activity is gram-positive microorganisms, and they do not develop resistance to this antimicrobial drug at all. It acts bactericidal by increasing the permeability of the cell cytoplasmic membrane.

Pharmacological group

Pharmacological group - antibiotics in combination with antiseptics.

Composition of children's Grammidin ®

The ingredient list of this medication, in addition to the antibiotic gramicidin in the chemical form of dihydrochloride 1.5 mg, includes the antiseptic compound cetylpyridinium chloride and formative elements. The listed components actively destroy pathogenic microflora in the throat and mouth and have a pleasant taste that children like.

Composition of drugs for adults

In addition to the drug Grammidin ® for children, there are two more types of these lozenges. Each of them basically contains the antibiotic gramicidin C ® as an active ingredient, but the additional ingredients differ.

• Grammidin Neo ® (“green scarf”) – antibacterial and antiseptic components (gramicidin and cetylpyridinium chloride 0.003 and 0.001 g each, respectively), silicon dioxide, flavoring additive, sweetener.
• Grammidin Neo ® with anesthetic - the same ingredients of antibacterial and antiseptic action in a similar volume, enhanced by an anesthetic (oxybuprocaine hydrochloride - 0.2 mg). Auxiliary components are similar in composition and quantity.

Photo of green packaging Grammidin ® “treats a sore throat” 18 tablets

Each carton contains 18 white biconvex tablets marked GR on one side.

What does Grammidin ® help with?

Typically, this dosage form of the antibiotic is prescribed for bacterial lesions of the mucous membranes of the mouth and throat. For stomatitis, sore throat and other infections, the drug has a local bactericidal effect, helping to reduce inflammation. The antiseptic cetylpyridinium chloride also destroys pathogenic microorganisms, and the anesthetic quickly eliminates pain and significantly improves well-being.

Indications for use of Grammidin ®

The basis for prescribing this medicine are infections caused by antibiotic-sensitive pathogens:

• tonsillitis (Grammidin Neo ® tablets are especially effective for sore throat);
• pharyngitis;
• stomatitis;
• gingivitis;
• periodontal disease.

The listed infectious diseases are usually treated with systemic drugs, and lozenges speed up the process due to hypersalivation (that is, increased salivation), which helps flush out pathogenic microflora.

Contraindications Grammidin ® for children

Due to the local use of the drug and low absorption rates, there are few prohibitions on use. These include phenylketonuria (due to the content of aspartame in the tablets), hypersensitivity to antibacterial drugs of the tyrothricine group and age less than two years. Grammidin ® for children, starting from 4 years of age, can be given in high concentrations (Neo or with an anesthetic).

Contraindications for adults

As in the case of the drug Grammidin ® for children, the main prohibition on the use of this ABP is individual intolerance to tyrothricin antibiotics and auxiliary components. In addition, Grammidin ® tablets should not be prescribed during pregnancy (in the first trimester) and during lactation. Also, “adult” dosage forms of the drug with an increased dosage are prohibited from being used to treat children under four years of age.

Dosages, regimens and duration of treatment

Both Grammidin ® for children and adults are intended for topical use by dissolving in the mouth until the tablet is completely dissolved. This is done immediately after eating, and in the future you need to abstain from food and drink for at least an hour (preferably two). This achieves maximum effectiveness of the active components due to their concentration and fixation on the mucous membranes.

Children, upon reaching 2 years of age, are prescribed Grammidin ® for children in the amount of 4 tablets per day (every 6 hours). It is not recommended to exceed the daily dosage to avoid side effects of the antibiotic. A child 4-12 years old can be prescribed other dosage forms of the drug (Neo or with an anesthetic) according to the same scheme: 4 times a day, one tablet.

Adults and adolescents, depending on the severity of the infection, should take either Grammidin Neo ® or the same drug with an anesthetic. The interval between main doses should also not be less than 6 hours, but you can use 2 tablets, dissolving them one after another (that is, eight pieces per day). If the result of antibiotic therapy does not appear for 2-3 days, you should contact your treating pediatrician or therapist to change the medication to an antibiotic of a different group.

Grammidin ® during pregnancy and breastfeeding

The drug is slightly adsorbed by the mucous membranes (gastrointestinal tract and oral cavity), therefore, it has virtually no systemic effect on the body. However, pregnant women between one and three months should not take it unless there are vital indications. Subsequently, Grammidin ® can be used during pregnancy. During the lactation period, it is advisable to abstain from treatment with antibiotics, however, if there is an urgent need, breastfeeding is stopped, and milk is expressed until the course of antibiotic therapy is completed.

Side effects of Grammidin ®

Grammidin ® for children may cause negative reactions such as stool disorders, vomiting or nausea, which quickly disappear when the drug is discontinued. Also, both children and adults may experience allergies in the form of local irritation. Taking medication with an anesthetic can cause temporary numbness in the mouth and loss of taste. As a rule, side effects occur extremely rarely and are completely reversible.

Grammidin ® for children and adults – reviews

Despite the fairly high price of the drug, most patients willingly buy it. For example, Grammidin ® for children currently costs about 260 rubles, but on the recommendation of a pediatrician, parents purchase this medicine and note its effectiveness with positive reviews. However, these tablets, as a rule, are prescribed to the child as part of complex therapy (in combination with systemic antibiotics, that is, tablets or injections).

According to most doctors, the treatment of bacterial respiratory tract infections with local antibacterial drugs is more likely to be a placebo than a real antibiotic therapy. In most cases, reviews of Grammidin ® with an anesthetic for adults indicate a short-term improvement in the condition, but not a cure for the underlying disease. For a couple of hours, the anesthetic substance dulls the painful symptoms of pharyngitis or sore throat, but subsequently they only intensify if systemic therapy is not carried out.

It turns out that lozenges “with a red scarf” are ineffective? No, local drugs in this case help to recover faster (in combination with systemic ones) due to increased secretion of saliva, which “washes away” pathogenic microorganisms. However, for the same reason, the anesthetic and antibiotic contained in the medicine do not stay on the mucous membrane for long.

About half of the buyers claim the high effectiveness of the drug, especially parents of children. And they also mention that Grammidin ® for children was prescribed in combination with other systemic drugs. Those adults who buy pills without a prescription, but in case of illness (without turning to a therapist) characterize the medicine as ineffective. To summarize, we can say that a visit to the doctor is the most important step on the path to recovery, and self-treatment with antibiotics only worsens the condition and leads to complications.