The use of eutirox for decreased thyroid function. "Eutirox": side effects of the drug

The modern market for medical drugs is wide and diverse. Consumers are offered medications of synthetic origin, herbal and hormonal products. One of the most frequently prescribed is the hormonal drug Eutirox.

Component composition and principle of operation

This drug can be described as a thyroid hormone preparation, which is a left-handed isomer of thyroxine. It was one of the first to be approved for use in European countries. Currently prescribed to patients in more than 70 countries around the world. The drug "Eutirox" stimulates the growth of muscle mass and tissue, accelerates metabolism. In small dosages, it makes protein synthesis in the body more effective and enhances calcification processes in bone tissue. Medium doses of the drug help the nervous and cardiovascular systems of the body work more actively, metabolic processes (fat, carbohydrate, protein) are accelerated. Body tissues require more oxygen. High doses of the drug inhibit the formation of a hormone produced by the pituitary gland, which, in turn, regulates the functioning of the thyroid gland.

Who is indicated for taking the drug?

The drug "Eutirox", the use of which must be supervised by a doctor, is prescribed in patients with diseases such as euthyroid goiter, a persistent lack of hormones produced by the thyroid gland in the body (hypothyroidism). In children, the extreme form of deficiency is cretinism. Next, the drug should be taken by those who have undergone surgery for oncological problems of the thyroid gland or have toxic goiter in a diffuse form. For preventive purposes (prevention of new manifestations), the drug "Eutirox" is prescribed to people who have undergone surgery on the thyroid gland. It is used as a diagnostic tool when performing a thyroid suppression test.

Contraindications

A strong indication to stop taking the drug is intolerance to its components. People suffering from thyrotoxicosis should not take the drug "Eutirox" (side effects will not be long in coming) if therapy with thyreostatics was insufficient. The presence of myocarditis and myocardial infarction is also a reason to refuse to take Eutirox. In addition, the drug is not prescribed to people suffering from acute pancarditis, untreated forms of pituitary insufficiency and adrenal insufficiency.

Patients with diabetes mellitus should take the drug carefully and under the strict supervision of an endocrinologist. Patients with dysfunctions of the cardiovascular system, suffering from atherosclerosis and severe forms of hypothyroidism should also be attentive to their condition. The doctor should also be careful when prescribing the drug to patients suffering from malabsorption syndrome.

Frequency of administration, dosage

Full information on how to take Eutirox is provided in the instructions accompanying the drug. In general, take the medicine once in the morning, the entire dose at once, at least 30 minutes before meals, and wash it down with water. The required daily dose depends on the disease and is selected by the attending physician. It is worth noting that in case of hypothyroidism, the drug “Eutirox” is indicated for lifelong use.

When treating goiter during the active period and after surgery, the prescribed dose of the drug ranges from 75 to 200 mcg. For thyrotoxicosis, the minimum volume is 50 mcg and can be increased to 100. When treating thyroid cancer, the dose of 50 mcg can be increased to 300. For hypothyroidism, the volume is calculated based on the patient’s age and depends on his weight. That is, a patient under the age of 55 can be prescribed a dose of up to 1.8 mcg per kilogram of weight. If the patient is over 55 years of age, the volume should not exceed 0.9 mcg per kg of weight.

When performing a thyroid suppression test, the dose depends on the period of time remaining before the procedure. 3-4 weeks before the test it is 75 mcg; for 2 - 100-150 mcg, for a week - 100-200 mcg. For children with congenital hypothyroidism, the dosage depends on age. Children under 6 months are prescribed 25-50 mcg, from 6 months to 1 year - 50-75 mcg, from one year to 5 years - 75-100 mcg, from 6 to 12 years - 100-150 mcg. For children over 12 years of age, the volume is 100-200 mcg.

When taking the hormonal drug Eutirox, side effects are quite possible, so patients should be attentive to their condition and contact their doctor at the first symptoms.

Exceeding the permissible dose, compatibility

According to reviews from patients and medical specialists, an overdose of Eutirox is manifested by a group of symptoms characteristic of thyrotoxicosis. The most striking manifestations of exceeding the dose include tachycardia, heart rhythm disturbances, and heart pain. On the part of the nervous system, tremor (hands shake), insomnia, restlessness, and increased sweating can be identified. Lack of normal appetite and, as a result, weight loss and diarrhea can also be caused by the drug "Eutirox". Overdose is treated by reducing the dose. Beta-blockers may be prescribed, or the use of hormones may be suspended for several days.

If the patient took extremely high doses of Eutirox, the doctor may prescribe plasmapheresis to relieve symptoms of overdose. In medical practice, there have been cases of cardiac arrest in patients who took maximum doses for several years. In some patients, convulsions occurred if the tolerance threshold for the drug Eutirox was exceeded. Reviews about the drug are quite mixed. But if symptoms associated with overdose occur, treatment should be resumed very carefully. The dose should be reduced relative to the one at which an overdose in one or another of its manifestations was diagnosed.

The drug "Eutirox" (instructions, patient reviews - direct proof of this) is not recommended to be combined with other medications without the appropriate prescription from the attending physician, because the medications may be incompatible.

Drugs

Manifestation of incompatibility

Indirect anticoagulants

The drug "Eutirox" can significantly enhance their effect

Tricyclic antidepressants

The effects of antidepressants may be significantly enhanced

Insulin and other drugs with similar effects

To achieve the desired effect, you need to increase the dose

Cardiac glycosides

The effectiveness of drugs weakens

Kelestyramine, colestipol, aluminum hydroxide

The concentration of levothyroxine in the blood plasma will be lower than necessary

Tamoxifen, anabolic steroids, asparanginase

Interaction at the level of connection with proteins is possible.

Phenytoin, salicylates, dicumarol, furosemide, clofibrate

The content of free levothyroxine, not bound to plasma proteins, increases

Some patients require increased levothyroxine levels

Somatotropin

The epiphyseal zones close faster than usual, stimulating growth

Carbamazeline, rifapmicin

The clearance of levothyroxine becomes higher

From all of the above, you can get an idea of ​​how an overdose of Eutirox manifests itself. Symptoms are usually pronounced, and measures must be taken immediately. And the right to combine the use of a hormonal drug with any other drug belongs only to the doctor.

For expectant mothers

For many women, the desire to become a mother is so strong that the doctor’s verdict that they cannot give birth due to the presence of some disease does not serve as a sufficient reason not to get pregnant. For a pregnant woman, the “success of the entire enterprise,” so to speak, may depend on taking medications prescribed by a doctor. When a future mother is diagnosed with a lack of hormones produced by the thyroid gland, the gynecologist prescribes the drug "Eutirox". During pregnancy, the drug must be taken continuously. It works instead of the thyroid gland, ensuring the normal functioning of the whole body. Canceling hormonal therapy for a woman and her unborn child is fraught with serious problems. Complications of intrauterine development, including mental retardation, are possible. Before synthetic analogues of thyroid hormones were developed, doctors recommended terminating a pregnancy for medical reasons.

Sometimes it happens that the expectant mother learns that the body does not have enough hormones produced by the thyroid gland only during the mandatory examination that all pregnant women undergo. In any case, the drug "Eutirox", the side effects of which can be quite painful, is vitally important to take. However, the intake should be under the supervision of the attending physicians - a gynecologist and an endocrinologist, because the dosage during the entire pregnancy may be changed depending on the results of TSH and blood tests. And both a lack of the hormone and its excess can have a bad effect on the child’s condition.

If a woman knew about the lack of hormones in the body even before pregnancy and took the drug "Eutirox", then when it occurs, the dose of the drug should be increased. After the baby is born and during the lactation period, the mother should continue taking the medication, but carefully and under the supervision of a doctor.

Shall we lose weight?

Those wishing to use the drug "Eutirox" for weight loss should first of all remember that this is a drug for thyroid hormones, and not a means for weight loss. Under no circumstances should you prescribe it to yourself! Small doses of the drug stimulate fat and protein metabolism, and a medium dosage has a positive effect on the functioning of the nervous and cardiovascular systems. The product is indicated for use for a fairly wide range of diseases, but nowhere does it say that it should be used for weight loss. This is a hormonal drug, and taking it without proper medical supervision can have the exact opposite effect - weight will increase.

In any case, those who take the drug “Eutirox” for weight loss should know that weight can decrease (that is, “may”, and not necessarily decrease) only for the reason that it speeds up metabolism, which is the reason for weight loss . Under no circumstances should you exceed the recommended dose. Such actions can have a very negative impact on health, disrupting the stable functioning of the heart, nervous system, and thyroid gland.

Medical experts do not recommend taking the drug "Eutirox" solely for the sake of losing weight. An inaccurate dosage can cause a lot of side and negative effects. If symptoms do appear, you should stop taking the drug for weight loss.

Side effects

In addition to the undoubted benefits in the treatment of diseases associated with insufficient production of thyroid hormones, the drug "Eutirox" has side effects. Its use can cause tachycardia (increased heartbeat), disrupt the rhythm of the heart and cause chest pain. The central nervous system may react to the drug with a disturbance in the general emotional background and insomnia. Manifestations such as significant weight loss, diarrhea, alopecia, impaired adrenal function in adults and impaired kidney function in children are quite possible.

Patients' opinions about the drug

The opinions of patients who have been taking Eutirox for quite a long time are very ambiguous. A separate group of people say that the drug brought them back to life. All symptoms accompanying a lack of thyroid hormones have gone away, and patients feel absolutely healthy. However, there is a considerable percentage of those who cannot refuse to take the drug, and simply do not have the strength to take it due to the large number of side effects.

Some patients complain of an increased feeling of anxiety, manifested in tremors, poor sleep, a feeling of fear, and depression. Many people complain of a constant feeling of cold and low body temperature. Some patients say that taking the drug increases dry cough, the skin becomes dry and cracks. However, if there are clear manifestations of hypothyroidism, choose the lesser of two evils - take the remedy.

For many expectant mothers, the leading doctor prescribes Eutirox during pregnancy. From some people the reviews are very positive, the condition is improving significantly. However, there are also those whose stomach reacts to taking the drug (constipation, constant nausea, lack of appetite), and herpes rashes appear.

Hormones of the endocrine gland are extremely necessary for humans. Synthetic analogues are able to replace hormones of the endocrine system in case of disruption of the gland, be responsible for normal cell growth, and regulate their renewal. The drug Eutirox is a medicinal analogue that has various pharmacological effects depending on the dosage.

The attending physician individually determines how to take Eutirox for hypothyroidism, taking into account the age, characteristics of the patient, in accordance with the duration and nature of the disease.

Thyroid gland and its hormones

The thyroid gland, called the thyroid gland in the 17th century, is located in the anterior part of the neck, next to it are the parathyroid glands. This small organ is a vulnerable place from the point of view of causing any injury or infection. The two lobes are connected by an isthmus, shaped like a shield. The gland, with its main endocrine function, is a participant in various processes of the body. Without the work of an organ, it is impossible to imagine the growth and development of any organism.

The main role of the thyroid gland, as it is popularly called, is the production of hormones:

  • thyroxine;
  • tyrosine;
  • Iodine tyranine.

Thyroxine stimulates the growth of the body as a whole, increasing resistance to high temperatures. It is produced from the intrauterine stage of human development. Without it, growth in height, development of mental abilities, and stabilization of the immune system do not occur. Under the influence of hormones, protection is enhanced - cells are more easily freed from foreign elements.

The production of hormones is regulated by higher glands - the hypothalamus and pituitary gland. The pituitary gland produces thyroid-stimulating hormone, which causes the thyroid gland to increase not only the production of iodothyranine and thyroxine, but also activates the growth of the gland itself. The hypothalamus is the control center where nerve impulses arrive. It produces hormones that regulate the activity of the pituitary gland.

Thus, under the guidance of the hypothalamus, throughout the day, the thyroid gland produces up to 300 micrograms of thyroid hormones, which ensure the development and construction of the nervous system. When the amount of hormones is excessive or insufficient, the nervous system responds with excitability or depression.

Eutirox for hypothyroidism

Characterized by a decrease in the concentration of the hormone in the blood. Often, hormonal deficiency is not detected for a long time, since the symptoms develop slowly and do not affect the general health, but occur under the masks of other diseases. With chronic deficiency, a person's metabolic processes slow down, resulting in a decrease in the production of energy and heat. The initial or obvious symptoms of hypothyroidism include:

  • chilliness;
  • loss of appetite with weight gain;
  • drowsiness;
  • dryness of the epidermis;
  • poor concentration, lethargy;
  • dizziness;
  • depression;
  • constipation;
  • cardiovascular disorders.

For deficient thyroid function, so-called hypothyroidism, Eutirox, a synthetic analogue of thyroxine, is primarily indicated. This drug is used for replacement purposes. The drug belongs to the category of iodine regulators in the body.

Clinical experience and recommendations show that the use of Eutirox for long-term replacement therapy is safe. The severity of situations varies. Sometimes the depth of the patient's experiences does not correspond to the severity of the problem that befell him. An exception to the rule is old age and concomitant pathologies:

  • adrenal insufficiency;
  • inflammation of the heart muscle;
  • acute myocardial infarction;
  • acute inflammation of the membranes of the heart;
  • atherosclerosis.

If you follow the recommendations in these cases, a dose adjustment of the drug is required. Eutirox is prescribed at 50 micrograms with further increases. Thyroxine is a hormone, and taking an artificial hormone, like taking any drug, is accompanied by side effects.

Effects of Eutirox

Eutirox is a hormonal tablet preparation that is chemically and molecularly identical to the human hormone. In case of hypothyroidism, which is accompanied by weight gain, the use of the drug leads to the fact that the function of the endocrine gland is normalized, and with good thyroxine levels, the weight is equalized. When taking a pharmaceutical product, allergic reactions are possible, which are detected in the initial stages of administration.

As for hair loss, when taking the drug, there is an improvement in hair quality, as opposed to the effects when hair loss is a symptom of insufficient function of the endocrine gland. When the condition passes, the hair will stop falling out, fragility and brittleness will disappear.

With an excess dose of the drug, signs of thyrotoxicosis appear - the opposite condition characterized by. The most common ones are:

  • arrhythmia;
  • high blood pressure;
  • insomnia;
  • irritability, short temper;
  • weight loss;
  • hyperhidrosis;
  • menstrual irregularities in women.

When the drug substance accumulates in the tissues of the body, changes in the functioning of the digestive system and allergic reactions also occur.

Taking and stopping Eutirox

To avoid side effects, Eutirox must be taken correctly:

  • early in the morning, usually half an hour before breakfast;
  • with a small portion of plain water.

It is advisable not to skip taking the drug, but to take it constantly, at the same time, throughout the entire period indicated by the doctor. Fluctuations in hormone levels are undesirable for the thyroid gland if the drug is missed. This can lead to the growth of gland nodes. You should not take the drug in a double dose to replace the missed one - this will cause a sharp jump in function. It is advisable to take the missed dose in the morning on the same day, at lunch or in the evening.

After removal of the thyroid gland, the prescription depends on the amount of tissue removed. If part of the gland has been resected or 50% of the tissue has been removed, the need to prescribe Eutirox is determined by the tests performed. This category of patients needs to check the level of thyroxine in the blood and determine the level of thyroid-stimulating hormone. If they are within normal limits, then the use of the drug is not mandatory. If decreased gland function is diagnosed - low levels of thyroxine or, conversely, an increase in thyroid-stimulating hormone, then replacement therapy is necessary.

If the thyroid gland is completely removed, the course of treatment covers the rest of your life. When prescribing Eutirox for the purpose of blocking the production of hormones by the thyroid gland itself, as a rule, the treatment course is determined for a specific period of 1–2 months.

When planning pregnancy, it is advisable to use the Eutirox hormone in the following cases:

  • if a woman has had a thyroid disease;
  • if you have undergone surgery on the gland and are prescribed replacement therapy.

With hypothyroidism, pregnancy is almost impossible. Carrying out adequate therapy with the prescription of hormonal drugs is the success of the development of pregnancy. During the period of gestation, taking a hormonal drug is mandatory for those for whom it is indicated. A woman who is pregnant and does not take replacement medications runs the risk of giving birth to a child with signs of thyroid insufficiency and mental retardation.

There are cases when it is necessary to increase the dose of Eutirox. Then the observation of such a pregnancy falls within the competence of not only the gynecologist, but also the endocrinologist. Children suffering from hormonal deficiency due to hypothyroidism also need to take this drug in the dosage and course as prescribed by a specialist. The portioned dose depends on the child’s body weight and age.

Self-discontinuation of the drug will lead to a new development of symptoms of hypothyroidism, when the production of thyroxine is impossible naturally. Cancellation of Eutirox while blocking hormonal production will not lead to pronounced changes.

Drug overdose

Taking Eutirox will bring hormone levels back to normal only in situations where it is justifiably prescribed. There is no need to be afraid of taking hormones. You need to be wary of a lack of hormones. The drug Eutirox is inexpensive, accessible and effective.

Secret area

There is only one point to pay attention to. A normal person without signs of hypothyroidism is able to work for 3 days in a row and then recover quietly for 2 days. A person who takes the artificial hormone levothyroxine has a hard time tolerating this condition. With an active lifestyle, with increased physical and emotional stress, a large dose of the hormone is required. In case of an overdose of Eutirox in case of hypothyroidism, problems with the functioning of the heart arise during the recovery period after workload:

  • increased heart rate;
  • tachycardia;
  • arrhythmia;
  • heartache.

The effect that a hormone similar in its chemical properties has in tablets to “native” thyroxine in a state of excitement remains unknown and is being studied by medicine, as well as pharmacology. Opinions tend to favor the effect of the body processing the artificial analogue. Nevertheless, the drug fully performs its function, and the most important tasks remain nuanced. People taking Eutirox work and rest safely, reproduce and raise healthy offspring.

Combination with other dosage forms

An overdose of thyroxine or an increase in the effect of the drug can occur with the use of certain products and dosage forms. If the dose was exceeded when taking Eutirox, the following symptoms appear:

  • chest discomfort;
  • dyspnea;
  • convulsions;
  • loss of appetite;
  • disruptions in the menstrual cycle;
  • sleep disturbance;
  • fever and excessive sweating;
  • diarrhea;
  • vomit;
  • rash;
  • irritability.

Taking herbal decoctions and vitamin complexes is carried out after consultation with an endocrinologist.

The medicine becomes poison for the body when acute signs of overdose are observed, appearing within 24 hours:

  • , in which an increase in all signs is obvious.
  • Mental disorders - convulsive seizures, delirium and semi-fainting states, leading to the development of coma.
  • A sharp decrease in urine output (anuria).
  • Liver atrophy.

Despite the fact that Eutirox is a drug that regulates iodine in the body, you can take iodine-containing synthetic (Iodomarin) or natural (kelp) forms. contains inorganic iodine, which is not produced in the body, and therefore must come from outside. This is especially important for pregnant women and people suffering from insufficiency of the endocrine gland.

Structural analogues

Trade analogues of the drug are represented by the names Bagotirox, Tireot and Novotiral. Despite the fact that all these pharmacological products share one active ingredient - levothyraxine, there are differences in their action. Eutirox, when taken as prescribed, unlike other structural analogues, does not have (or in rare cases has) side effects. Indicated for the treatment of childhood deficiency conditions.

Combining with other drugs, prescribing or changing the dose on your own is strictly not recommended. Only a doctor, based on the physiological characteristics and individual health indicators of the patient, selects the drug, dosage and course of treatment.

First aid for overdose

When you feel the first signs of illness, you need to see a doctor or call a specialist to your home. You should not delay calling an ambulance if your condition worsens, or in the following cases:

  • if an overdose occurs in a child, pregnant woman, or elderly person;
  • serious heart rhythm disturbances and chest pain;
  • diarrhea with bloody discharge;
  • high blood pressure;
  • pathologies of a neurological nature - seizures, paralysis, paresis;
  • disturbances of consciousness.

Depending on the severity of intoxication, drug therapy is carried out using symptomatic drugs, blood purification procedures for unconscious patients.

Contents of the article: classList.toggle()">toggle

Eutirox is a hormonal drug whose active ingredient is sodium levothyroxine. Most often, this drug is used in the treatment or replacement therapy for thyroid diseases. An overdose of eutirox can lead to a number of serious pathologies.

How does the drug affect the body? How serious are the consequences of an excess of hormones as a result of taking eutirox? Is it possible to develop withdrawal syndrome? You will read about this and much more in our article.

The use of eutirox and the effect of the drug on the body

Levothyroxine sodium belongs to a fairly broad pharmacological group of thyroid drugs in the form of artificial thyroid and parathyroid hormones. Thus, the main medicine affects the body identically to its physiological counterpart in the form of a secretion.

The functional activity of exogenous eutirox in comparison with the endogenous hormone coincides up to tenths of a percent - both penetrate into peripheral tissues, where they are converted into triiodothyronine, which in turn has a positive effect on metabolism, growth and synthesis of new tissues, the activity of the central nervous system and the cardiovascular system.

Eutirox is prescribed for classic hypothyroidism, goiter of the euthyroid and diffuse-toxic type, as well as as the main replacement therapy or prevention of goiter relapse after surgery with resection of part of the thyroid gland or the entire organ as a whole.

In addition, the drug acts as an element of treatment in the case of the presence of malignant formations in the thyroid gland, as well as as a diagnostic tool in cases of conducting a comprehensive test of thyroid suppression.

The dosage of the drug depends on the type of treatment:

Overdose symptoms

An overdose of eutirox causes a symptomatic complex in the victim that is almost identical to the classic manifestations of hyperthyroidism, and its severity depends on the amount of the drug consumed:

  • Increased blood pressure, up to critical values ​​in severe overdose;
  • Tachycardia. From 120 beats per minute and above;
  • Severe pain syndrome. Pain in the head (mainly from the back of the head) and dizziness, even fainting;
  • Anxiety, sudden panic attacks, irritability;
  • Dyspeptic disorders. Nausea with vomiting, pain in the epigastric region, profuse diarrhea, intestinal colic, flatulence, unpleasant belching;
  • Trembling in the limbs. In severe forms of poisoning – convulsions throughout the body;
  • Other manifestations. In the case of particularly severe forms of hormone overdose, the risks of developing myocardial infarction, stroke and complete cardiac arrest significantly increase.

First aid and body recovery

A victim of an overdose of eutirox must be provided with all possible first aid, and then call a medical team to assess the person’s current condition - in case of severe poisoning, he will be promptly taken to the intensive care unit or an endocrinology clinic.

First aid measures:


Similar articles

Upon arrival of the ambulance team, doctors may decide to transport the victim to the endocrinology department or intensive care unit. There, he will undergo standard detoxification procedures, support vital signs, and be prescribed symptomatic and corrective conservative therapy.

Consequences and complications after overdose

Both chronic and acute overdose of eutirox can cause a number of long-term pathological consequences in a person in the form of associated complications. The most typical of them:


Drug withdrawal syndrome

Eutirox is prescribed exclusively by a specialized endocrinologist as part of a course of therapy. If we are not talking about a constant lifelong need for this drug (against the background of dystrophy, resection and other pathologies of the thyroid gland, which forever ceases to produce thyroxine and other necessary substances), then sooner or later the drug is withdrawn from the treatment procedure.

As clinical practice shows, abrupt withdrawal of eutyrox provokes strong pathological symptoms that generally coincide with the manifestations of hypothyroidism.

Eutirox withdrawal syndrome may be accompanied by the following consequences:


The effects of drug withdrawal can be neutralized only under the supervision of an endocrinologist., who will prescribe special replacement therapy and indicate the timing of a gradual reduction in the dose of eutirox taken, both qualitatively and quantitatively.

Overdose of eutirox for hypothyroidism

Overdose of hormonal drugs, including eutirox, in hypothyroidism in the vast majority of cases occurs as a result of self-correction of daily doses of the drug towards an increase. In this case, there are usually no acute symptoms, and clinicopathological manifestations develop over weeks and generally coincide with the classic picture of hyperthyroidism.

Treatment of hypothyroidism consists of a reasonable reduction in the dose of the main drug, carrying out replacement therapy, in rare cases - plasmapheresis and other actions aimed at quickly reducing the concentration of the active substance, both in the main bloodstream and in peripheral tissues.

Synthetic thyroxine (levothyroxine sodium) is used to treat hypothyroidism (low thyroid function) and some other conditions. Many trade names of this drug are registered in Russia. Synthetic thyroxine is presented under the brands “L-Thyroxin-Farmak”, “L-Thyroxine”, “L-Thyroxine Berlin Hemi”, “Bagotiroks”, “Eutirox”, “L-Tyrok”, “Sodium levothyroxine”, “L-Thyroxine” -Acri”, “L-Thyroxine Hexal”, etc.

One of the most popular drugs on the market is Eutirox. Thousands of patients with hypothyroidism buy it in a dose of 25 mcg. Most often, doctors recommend 50-100 mcg tablets.

Eutirox is produced by a German pharmaceutical company. This drug is considered high quality, effective and safe. If the pills are prescribed by a doctor, then there are practically no side effects.

Adverse events when taking Eutirox

"Eutirox" is a hormonal drug. Under no circumstances should it be taken without consultation with an endocrinologist or a doctor of another specialty. Even small doses (25–50 mcg) can cause complications.

Side effects from these tablets primarily include allergies.

Individual sensitivity to the components of the drug is observed with excessive reactivity of the immune system. Allergies are a manifestation of an imbalance of defenses in the body.

A reaction to the tablets may be related to levothyroxine sodium itself. Also, auxiliary components (gelatin, starch, lactose, magnesium stearate, etc.) can also cause allergies.

Individual sensitivity to the components of the tablet is a reason to change the drug to an analogue. If the patient is not suitable for any drug of levothyroxine sodium (allergy to the active substance), then other medications are recommended. You can replace thyroxine with tablets containing synthetic triiodothyronine. Such a change in medications should only occur under the supervision of a physician.

Allergies can have different manifestations. Life-threatening conditions such as anaphylaxis develop extremely rarely. Skin itching, rashes, urticaria, etc. are more common. Allergies can also be in the form of conjunctivitis, runny nose, swelling of soft tissues, changes in hair structure, alopecia (hair loss).

Hair loss while taking Eutirox can be quite massive. This effect is especially troubling for women. Hair loss as an allergic reaction begins a few days or weeks after the start of hormone replacement therapy. The dose of the drug does not matter much. Hair loss can be caused by 25 mcg, 50 mcg, or a large dose of levothyroxine.

Alopecia due to pills must be distinguished from baldness due to hypothyroidism. If a patient experiences hair loss while taking levothyroxine, and the TSH (thyrotropin) test is higher than normal, then the cause of the problem is a lack of the hormone. In this case, it is necessary to increase the dose of Eutirox by 25–50 mcg. After a few weeks, hair loss should stop.

Hair problems cannot always be explained by thyroid disease. It is known that loss can also occur with other hormonal imbalances, lack of vitamins, microelements, etc. Even acute or chronic stress can trigger hair loss. To determine the cause, it is advisable to visit a specialist - a trichologist. The doctor will assess the condition of the hair, prescribe diagnostics and treatment.

Overdose of "Eutirox"

Side effects from an overdose of Eutirox are associated with errors in the scheme. Excess of the drug may be accidentally recommended by the doctor. Sometimes patients increase the dose of tablets on their own.

Daily consumption of an extra 25–50 mcg of levothyroxine sodium provokes unpleasant effects. Patients experience rapid heartbeat. If you count the pulse at such a moment, the number of heartbeats will exceed 90 per minute. Many also have complaints of arrhythmia. An irregular pulse can be felt in the form of pauses or “slips”. With an undesirable effect on the heart muscle, ischemia occurs in some patients. Insufficient blood supply to the myocardium provokes chest pain, shortness of breath at rest and during physical activity.

The effect of an extra 25–50 mcg on the nervous system can lead to side effects: tremors in the fingers, sleep disturbances, panic attacks.

Damage to the autonomic nervous system due to an overdose of thyroxine is manifested by sweating and a feeling of heat in the body.

Every 25–50 mcg of Eutirox increases the body's need for calories. Excess micrograms of the drug can lead to gradual weight loss, even against the background of a good appetite.

Other side effects from overdose include:

  • suppression of the adrenal glands;
  • functional disorders of the kidneys.

These conditions have several degrees of severity. Sometimes dysfunction of the kidneys and adrenal glands threatens the patient’s life.

To avoid an overdose of Eutirox, therapy is started with small doses (25–50 mcg). The effect of treatment is assessed by the patient’s well-being and laboratory tests. If the TSH level falls below the normal limit, the drug is considered an overdose. In this case, cancel Eutirox for several days. Then therapy is resumed at a lower dose (minus 12.5-25-50 mcg).

Adverse drug interactions

Side effects when using Eutirox may also be associated with drug interactions. If a person takes several different pills at once, they can affect each other’s effectiveness.

"Eutirox" reduces the effect of:

  • insulin injections;
  • sugar-lowering tablets;
  • cardiac glycosides.

The hormone has the opposite effect on tricyclic antidepressants and indirect anticoagulants. Even in a small dose of 25-50 mcg, it significantly enhances the effect of these drugs.

Post date: 15.12.2011 19:11

Tatiana

Hello! I had an appointment with you about 2 weeks ago. I took Eutirox 125 mg for 1.5 years. Two weeks ago I took tests: you said T4 was normal, and TSH was 0.01. You canceled Eutirox completely and told me to come back for tests in early January. During these two weeks, the weight has increased by 5 kg??? maybe at least reduce the dosage? What do you think?

Post date: 15.12.2011 21:42

Stavina V.M.

Good evening. In such a short period of time of stopping eutirox (subject to your hormone levels), weight cannot increase so dramatically. Perhaps something has changed in your diet? You need to look at the level of hormones against a clear background, and if you take eutirox, even in a reduced dose, this is the work of the pills. There is an option - take hormones early.

Post date: 16.12.2011 17:16

Tatiana

Thank you very much. And please tell me more about my 8-year-old son. Tests were taken: T4W - 14.1, TSH - 0.702. Tell me, is this normal or should I come to an appointment?

Post date: 16.12.2011 20:14

Post date: 18.09.2012 14:43

Guest

Is it possible to cancel Eutirox after 5 years of taking it? TSH normal Ultrasound normal no changes 5 years

Post date: 15.06.2013 10:44

Olga

Good afternoon Throughout the pregnancy I took eutirox 50 mcg, while taking the tablets my TSH was normal. After giving birth, a month later I took a test for TSH - 0.07. Can I suddenly stop taking eutirox, or should I gradually reduce the dose. How will this affect the baby, is he breastfed? thank you in advance!

Post date: 23.10.2014 13:32

Susie

Hello. I am 7 months pregnant. I have antibodies to TPO 522. The endocrinologist prescribed eutyrox50 in the following dosage: 4 days-1/4, 4 days-1/2, 4 days-a whole tablet. after taking it, nausea lasted the whole day. Pink discharge appeared. Is this related to taking eutirox? and how does taking this hormone generally affect the child? Will I gain weight with this dosage? Thanks in advance

Post date: 08.05.2015 21:32

Lyudmila

an 11-year-old child has antibodies to TPO 290.5 TSH 0.38
FT4 20.2
We take Eutirox 56.25 mcg - could this be a large dosage?

Post date: 31.12.2015 08:41

Natalia

Hello. My mother has been taking Eutirox for about two years. Now her pressure surges have sharply worsened and problems with her pancreas have appeared. Her hormones are normal (diagnosed with multinodular goiter). She wants to stop taking this drug. Tell me how best to do this

Post date: 31.12.2015 10:26

Guest

Hello. My mother has been taking Eutirox for about two years. Now her pressure surges have sharply worsened and problems with her pancreas have appeared. Her hormones are normal (diagnosed with multinodular goiter). She wants to stop taking this drug. Tell me how best to do this?

Post date: 13.05.2016 11:47

Tatiana

Hello, Diagnosis of mixed goiter, I took Eutirox 25 mg for six months, the weight increased critically, I gained 8 kg, pressure surges appeared, pulse jumped to 150 beats, arrhythmia, joint pain: Now I have not been taking Eutirox for two weeks, is it possible to abruptly stop the drug?

Post date: 23.07.2016 14:55

Lola

Hello. I have a question. My sister is taking Eutyrox 25 mcg. already 1 month old, she is 12 years old..ultrasound, signs of anatomy..length 48mm, thickness 17mm.width 14mm.volume 5.5cm3.left length 44mm.thickness 13mm.width 13mm.volume 3.6cm3.isthmus 4.0mm.total volume 9.1cm3. ttg5.07.

Post date: 23.07.2016 14:58

Lola

Is it possible to stop taking these pills?

Post date: 13.12.2016 19:38

Vera Ivanovna

TSH-2.9. Hypothyroidism. Took Alba. If you get nervous, even a little bit, immediately some kind of lump puts pressure on the thyroid gland. Without a doctor’s prescription, I started taking eutirox from 25 to 100 units. A year later, my heart began to thump. The TSH indicator was 0.004. I reduced the dose to 12. The heart sometimes still reminds itself of itself in the same way, but mostly it’s better. How to completely stop taking eutirox if 12 units. Have I been drinking for 30 days?

Post date: 02.02.2017 05:59

Guest

Hello. My husband was prescribed Eutirox 75. He has been taking pills for 5 months. At the time of appointment the level was 8.75. This month we took tests and it showed 22.35. Why did it happen? Is it possible to temporarily stop taking Eutyrox?